IR@PKUHSC  > 北京大学基础医学院  > 生理学与病理生理学系
学科主题基础医学
beta-Endorphin- and GABA-mediated depressor effect of specific electroacupuncture surpasses pressor response of emotional circuit
Ku, YH; Chang, YZ
关键词blood pressure emotion stress central nervous system beta-endorphin GABA acupuncture
刊名PEPTIDES
2001-09-01
22期:9页:1465-1470
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
研究领域[WOS]Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
关键词[WOS]CENTRAL AMYGDALOID NUCLEUS ; CORTICOTROPIN-RELEASING FACTOR ; CARDIOVASCULAR-RESPONSES ; SUBSTANCE-P ; NEURONS ; STRESS ; RAT ; ENDOCRINE ; BEHAVIOR ; SYSTEM
英文摘要

It has been proved that input of specific electroacupuncture (EA) can activate beta -endorphin(beta -EP)ergic and noradrenergic neurons projecting to the rostra[ ventrolateral medulla (RVL), the latter acting upon the RVL-GABAergic interneurons, thereby produce depressor effect. The present study further shows that: (1) The EA depressor effect is strong enough to surpass the pressor response of the AC (nucleus amygdaloideus central is) -emotional circuit, (2) both beta -endorphin (beta -EP) and GABA in the RVL mediate the EA antagonistic effect, (3) the EA effect does not take place in the AC and paraventricular nucleus (two key nuclei besides the RVL, which also have beta -EPergic input) in the emotional circuit. (C) 2001 Elsevier Science Inc. All rights reserved.

语种英语
WOS记录号WOS:000170561200016
Citation statistics
Cited Times:22[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65496
Collection北京大学基础医学院_生理学与病理生理学系
作者单位Beijing Univ, Hlth Sci Ctr, Dept Physiol, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Ku, YH,Chang, YZ. beta-Endorphin- and GABA-mediated depressor effect of specific electroacupuncture surpasses pressor response of emotional circuit[J]. PEPTIDES,2001,22(9):1465-1470.
APA Ku, YH,&Chang, YZ.(2001).beta-Endorphin- and GABA-mediated depressor effect of specific electroacupuncture surpasses pressor response of emotional circuit.PEPTIDES,22(9),1465-1470.
MLA Ku, YH,et al."beta-Endorphin- and GABA-mediated depressor effect of specific electroacupuncture surpasses pressor response of emotional circuit".PEPTIDES 22.9(2001):1465-1470.
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