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学科主题: 药学
题名:
Aquisiflavoside, a new nitric oxide production inhibitor from the leaves of Aquilaria sinensis
作者: Yang, Xin-Bao1,2,3; Feng, Jie1; Yang, Xiu-Wei1; Zhao, Bo1; Liu, Jian-Xun2,3
关键词: Aquilaria sinensis ; aquisiflavoside ; flavonoid ; nitric oxide
刊名: JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
发表日期: 2012
DOI: 10.1080/10286020.2012.701209
卷: 14, 期:9, 页:867-872
收录类别: SCI ; IC
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]: Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
英文摘要:

A new flavonoid glycoside, named aquisiflavoside, was isolated from the leaves of Aquilaria sinensis (Lour.) Gilg, and its structure was elucidated by spectroscopic analyses. Aquisiflavoside was evaluated for the inhibition of nitric oxide (NO) production induced by lipopolysaccharide in macrophage cell line RAW 264.7 and exhibited a potent inhibitory activity against NO production in a dose-dependent manner with an IC50 value of 34.95 mu M.

语种: 英语
所属项目编号: 2011BAI07B08 ; 2006BAI 06A01-02
项目资助者: National Key Technology R&amp ; D Program of China
WOS记录号: WOS:000308984000008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65501
Appears in Collections:北京大学药学院_天然药物学系_期刊论文

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作者单位: 1.Peking Univ, Sch Pharmaceut Sci, Dept Nat Med, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Beijing Univ Chinese Med, Beijing 100029, Peoples R China
3.China Acad Chinese Sci, Xiyuan Hosp, Beijing 100091, Peoples R China

Recommended Citation:
Yang, Xin-Bao,Feng, Jie,Yang, Xiu-Wei,et al. Aquisiflavoside, a new nitric oxide production inhibitor from the leaves of Aquilaria sinensis[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2012,14(9):867-872.
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