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Aquisiflavoside, a new nitric oxide production inhibitor from the leaves of Aquilaria sinensis
Yang, Xin-Bao1,2,3; Feng, Jie1; Yang, Xiu-Wei1; Zhao, Bo1; Liu, Jian-Xun2,3
关键词Aquilaria sinensis aquisiflavoside flavonoid nitric oxide
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
2012
DOI10.1080/10286020.2012.701209
14期:9页:867-872
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
资助者National Key Technology R&amp ; D Program of China ; National Key Technology R&amp ; D Program of China
研究领域[WOS]Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
英文摘要

A new flavonoid glycoside, named aquisiflavoside, was isolated from the leaves of Aquilaria sinensis (Lour.) Gilg, and its structure was elucidated by spectroscopic analyses. Aquisiflavoside was evaluated for the inhibition of nitric oxide (NO) production induced by lipopolysaccharide in macrophage cell line RAW 264.7 and exhibited a potent inhibitory activity against NO production in a dose-dependent manner with an IC50 value of 34.95 mu M.

语种英语
所属项目编号2011BAI07B08 ; 2006BAI 06A01-02
资助者National Key Technology R&amp ; D Program of China ; National Key Technology R&amp ; D Program of China
WOS记录号WOS:000308984000008
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65501
专题北京大学药学院_天然药物学系
作者单位1.Peking Univ, Sch Pharmaceut Sci, Dept Nat Med, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Beijing Univ Chinese Med, Beijing 100029, Peoples R China
3.China Acad Chinese Sci, Xiyuan Hosp, Beijing 100091, Peoples R China
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GB/T 7714
Yang, Xin-Bao,Feng, Jie,Yang, Xiu-Wei,et al. Aquisiflavoside, a new nitric oxide production inhibitor from the leaves of Aquilaria sinensis[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2012,14(9):867-872.
APA Yang, Xin-Bao,Feng, Jie,Yang, Xiu-Wei,Zhao, Bo,&Liu, Jian-Xun.(2012).Aquisiflavoside, a new nitric oxide production inhibitor from the leaves of Aquilaria sinensis.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,14(9),867-872.
MLA Yang, Xin-Bao,et al."Aquisiflavoside, a new nitric oxide production inhibitor from the leaves of Aquilaria sinensis".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 14.9(2012):867-872.
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