|Association of Heart Rate Variability in Taxi Drivers with Marked Changes in Particulate Air Pollution in Beijing in 2008|
|Wu, Shaowei; Deng, Furong; Niu, Jie2; Huang, Qinsheng2; Liu, Youcheng3; Gu, Xinbiao1|
|关键词||air pollution cardiac autonomic function epidemiology heart rate variability particulate matter|
|刊名||ENVIRONMENTAL HEALTH PERSPECTIVES|
|WOS标题词||Science & Technology|
|类目[WOS]||Environmental Sciences ; Public, Environmental & Occupational Health ; Toxicology|
|研究领域[WOS]||Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Toxicology|
|关键词[WOS]||CARDIAC AUTONOMIC CONTROL ; ENVIRONMENTAL EXPOSURE ; EPIDEMIOLOGIC EVIDENCE ; ELDERLY SUBJECTS ; MEXICO-CITY ; DISEASE ; STRESS ; DEATH ; MORTALITY ; WORKERS|
BACKGROUND: Heart rate variability (HRV), a marker of cardiac autonomic function, has been associated with particulate matter (PM) air pollution, especially in older patients and those with cardiovascular diseases. However, the effect of PM exposure on cardiac autonomic function in young, healthy adults has received less attention.
OBJECTIVES: We evaluated the relationship between exposure to traffic-related PM with an aerodynamic diameters <= 2.5 mu m (PM(2.5)) and HRV in a highly exposed panel of taxi drivers.
METHODS: Continuous measurements of personal exposure to PM(2.5) and ambulatory electrocardiogram monitoring were conducted on I I young healthy taxi drivers for a 12-hr work shift during their work time (0900-2100 hr) before, during, and after the Beijing 2008 Olympic Games. Mixed-effects regression models were used to estimate associations between PM(2.5) exposure and percent changes in 5-min HRV indices after combining data from the three time periods and controlling for potentially confounding variables.
RESULTS: Personal exposures of taxi drivers to PM(2.5) changed markedly across the three time periods. The standard deviation of normal-to-normal (SDNN) intervals decreased by 2.2% [95% confidence interval (0), -3.8% to -0.6%] with an interquartile range (IQR; 69.5 mu g/m(3)) increase in the 30-min PM(2.5) moving average, whereas the low-frequency and high-frequency powers decreased by 4.2% (95% CI, -9.0% to 0.8%) and 6.2% (95% CI, -10.7% to -1.5%), respectively, in association with an IQR increase in the 2-hr PM(2.5) moving average.
CONCLUSIONS: Marked changes in traffic-related PM(2.5) exposure were associated with altered cardiac autonomic function in young healthy adults.
|项目编号||2006BA119B06 ; 30571534|
|资助机构||National Key Technologies R& ; D Program of China ; National Natural Science Foundation of China|
|作者单位||1.Peking Univ, Hosp 3, Beijing 100191, Peoples R China|
2.Univ Kentucky, Coll Publ Hlth, Lexington, KY USA
3.Peking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth Sci, Beijing 100191, Peoples R China
|Wu, Shaowei,Deng, Furong,Niu, Jie,et al. Association of Heart Rate Variability in Taxi Drivers with Marked Changes in Particulate Air Pollution in Beijing in 2008[J]. ENVIRONMENTAL HEALTH PERSPECTIVES,2010,118(1):87-91.|
|APA||Wu, Shaowei,Deng, Furong,Niu, Jie,Huang, Qinsheng,Liu, Youcheng,&Gu, Xinbiao.(2010).Association of Heart Rate Variability in Taxi Drivers with Marked Changes in Particulate Air Pollution in Beijing in 2008.ENVIRONMENTAL HEALTH PERSPECTIVES,118(1),87-91.|
|MLA||Wu, Shaowei,et al."Association of Heart Rate Variability in Taxi Drivers with Marked Changes in Particulate Air Pollution in Beijing in 2008".ENVIRONMENTAL HEALTH PERSPECTIVES 118.1(2010):87-91.|