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学科主题: 口腔医学
题名:
Survival Analysis of Oral Squamous Cell Carcinoma in a Subgroup of Young Patients
作者: Fan, Yi1; Zheng, Lei1; Mao, Ming-Hui1; Huang, Ming-Wei1; Liu, Shu-Ming1; Zhang, Jie1; Li, Sheng-Lin2; Zheng, Lei1; Zhang, Jian-Guo1
关键词: Oral squamous cell carcinoma ; oral cavity ; survival ; young patients ; tobacco ; alcohol
刊名: ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
发表日期: 2014
DOI: 10.7314/APJCP.2014.15.20.8887
卷: 15, 期:20, 页:8887-8891
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology
研究领域[WOS]: Oncology
关键词[WOS]: HUMAN-PAPILLOMAVIRUS ; RISK-FACTORS ; CLINICOPATHOLOGICAL FEATURES ; NEVER-DRINKERS ; TONGUE ; CANCER ; SMOKERS ; PEOPLE ; ADULTS ; HEAD
英文摘要:

Oral squamous cell carcinoma (OSCC) is predominantly a disease of middle-aged men with long-term exposure to tobacco and alcohol. An increasing trend has been reported at a younger age worldwide. Clinical records of 100 patients under the age of 45 years treated specifically for oral cavity SCC in our hospital during a 10-year period were retrospectively analyzed to calculate the survival rates. An obvious male predominance coincided with smoking trend among Chinese young individuals and female patients were more likely to have no traditional risk factors such as smoking or drinking. The 5-year overall survival rate and disease-free survival rate were 61.0% and 75.5%, respectively, consistent with other published series over the decade showing a relatively better survival among the young. No significant differences clearly correlated with outcome when comparing non-smokers non-drinkers to ever-smokers and ever drinkers (P>0.05). Overall survival rate and disease free survival rate was found to be significantly higher in patients with early-stage disease than with advanced stage disease (P=0.001, P=0.009 respectively). The strong influence of clinical stage on prognosis emphasizes the importance of early diagnosis and treatment of oral malignancies for this unique clinical subgroup.

语种: 英语
WOS记录号: WOS:000351055100061
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65533
Appears in Collections:北京大学口腔医学院_期刊论文

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作者单位: 1.Peking Univ, Sch & Hosp Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100871, Peoples R China
2.Peking Univ, Sch & Hosp Stomatol, Cent Lab, Beijing 100871, Peoples R China

Recommended Citation:
Fan, Yi,Zheng, Lei,Mao, Ming-Hui,et al. Survival Analysis of Oral Squamous Cell Carcinoma in a Subgroup of Young Patients[J]. ASIAN PACIFIC JOURNAL OF CANCER PREVENTION,2014,15(20):8887-8891.
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