IR@PKUHSC  > 北京大学口腔医学院
学科主题口腔医学
Survival Analysis of Oral Squamous Cell Carcinoma in a Subgroup of Young Patients
Fan, Yi1; Zheng, Lei1; Mao, Ming-Hui1; Huang, Ming-Wei1; Liu, Shu-Ming1; Zhang, Jie1; Li, Sheng-Lin2; Zheng, Lei1; Zhang, Jian-Guo1
关键词Oral squamous cell carcinoma oral cavity survival young patients tobacco alcohol
刊名ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
2014
DOI10.7314/APJCP.2014.15.20.8887
15期:20页:8887-8891
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Oncology
研究领域[WOS]Oncology
关键词[WOS]HUMAN-PAPILLOMAVIRUS ; RISK-FACTORS ; CLINICOPATHOLOGICAL FEATURES ; NEVER-DRINKERS ; TONGUE ; CANCER ; SMOKERS ; PEOPLE ; ADULTS ; HEAD
英文摘要

Oral squamous cell carcinoma (OSCC) is predominantly a disease of middle-aged men with long-term exposure to tobacco and alcohol. An increasing trend has been reported at a younger age worldwide. Clinical records of 100 patients under the age of 45 years treated specifically for oral cavity SCC in our hospital during a 10-year period were retrospectively analyzed to calculate the survival rates. An obvious male predominance coincided with smoking trend among Chinese young individuals and female patients were more likely to have no traditional risk factors such as smoking or drinking. The 5-year overall survival rate and disease-free survival rate were 61.0% and 75.5%, respectively, consistent with other published series over the decade showing a relatively better survival among the young. No significant differences clearly correlated with outcome when comparing non-smokers non-drinkers to ever-smokers and ever drinkers (P>0.05). Overall survival rate and disease free survival rate was found to be significantly higher in patients with early-stage disease than with advanced stage disease (P=0.001, P=0.009 respectively). The strong influence of clinical stage on prognosis emphasizes the importance of early diagnosis and treatment of oral malignancies for this unique clinical subgroup.

语种英语
WOS记录号WOS:000351055100061
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65533
专题北京大学口腔医学院
北京大学口腔医学院_外科
作者单位1.Peking Univ, Sch & Hosp Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100871, Peoples R China
2.Peking Univ, Sch & Hosp Stomatol, Cent Lab, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Fan, Yi,Zheng, Lei,Mao, Ming-Hui,et al. Survival Analysis of Oral Squamous Cell Carcinoma in a Subgroup of Young Patients[J]. ASIAN PACIFIC JOURNAL OF CANCER PREVENTION,2014,15(20):8887-8891.
APA Fan, Yi.,Zheng, Lei.,Mao, Ming-Hui.,Huang, Ming-Wei.,Liu, Shu-Ming.,...&Zhang, Jian-Guo.(2014).Survival Analysis of Oral Squamous Cell Carcinoma in a Subgroup of Young Patients.ASIAN PACIFIC JOURNAL OF CANCER PREVENTION,15(20),8887-8891.
MLA Fan, Yi,et al."Survival Analysis of Oral Squamous Cell Carcinoma in a Subgroup of Young Patients".ASIAN PACIFIC JOURNAL OF CANCER PREVENTION 15.20(2014):8887-8891.
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