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学科主题: 药学
题名:
Comparative study of chemical constituents of rhubarb from different origins
作者: Komatsu, Katsuko; Nagayama, Yorinobu; Tanaka, Ken; Ling, Yun; Cai, Shao-Qing; Omote, Takayuki; Meselhy, Meselhy Ragab
关键词: Rhei Rhizoma ; Rheum ; genetic variety ; HPLC ; quantitative comparison
刊名: CHEMICAL & PHARMACEUTICAL BULLETIN
发表日期: 2006-11-01
卷: 54, 期:11, 页:1491-1499
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
研究领域[WOS]: Pharmacology & Pharmacy ; Chemistry
关键词[WOS]: RHEI-RHIZOMA ; PHYLOGENETIC RELATIONSHIP ; TANNINS ; IDENTIFICATION ; GLYCOSIDES ; DRUGS ; GENE
英文摘要:

A comparative study of the pharmacologically active constituents of 24 rhubarb samples, which were identified genetically as Rheum tanguticum, 3 intraspecies groups of R. palmatum and R. officinale, was conducted using reversed-phase high performance liquid chromatography (HPLC) methods. Thirty compounds belonging to anthraquinones, anthraquinone glucosides, dianthrones, phenylbutanones, stilbenes, flavan-3-ols, procyanidins, galloylglucoses, acylglucoses, gallic acid, and polymeric procyanidins were analyzed quantitatively. The drug samples derived from the same botanical source showed similar chromatographic profiles, and the comparable specific shape that appeared in the 10-directed radar graphs constructed on the basis of the results of quantitative analysis indicated the relationship between chemical constituent patterns and genetic varieties of rhubarb samples.

语种: 英语
WOS记录号: WOS:000242481000003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65562
Appears in Collections:北京大学药学院_天然药物学系_期刊论文

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作者单位: 1.Toyama Univ, Inst Nat Med, Dept Med Resources, Div Pharmacognosy, Toyama 9300194, Japan
2.Peking Univ, Sch Pharmaceut Sci, Dept Nat Med, Beijing 100083, Peoples R China
3.Cairo Univ, Fac Pharm, Dept Pharmacognosy & Med Plants, Cairo, Egypt
4.Toyama Univ, Century COE Program 21st, Toyama 9300194, Japan
5.Yanjing Hosp, Beijing 100083, Peoples R China

Recommended Citation:
Komatsu, Katsuko,Nagayama, Yorinobu,Tanaka, Ken,et al. Comparative study of chemical constituents of rhubarb from different origins[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2006,54(11):1491-1499.
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