IR@PKUHSC  > 北京大学公共卫生学院
学科主题公共卫生
Increased Arterial Stiffness in Subjects with Pre-diabetes among Middle Aged Population in Beijing, China
Shen Li1; Zhang Yan Ge2; Liu Min1; Wu Liu Xin2; Qiang Dong Chang2; Sun Xue Lei2; Liu Lin2; Jiang Yuan Yuan2
关键词Pre-diabetes Vascular stiffness Arterial stiffness
刊名BIOMEDICAL AND ENVIRONMENTAL SCIENCES
2013-09-01
DOI10.3967/0895-3988.2013.09.002
26期:9页:717-725
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Environmental Sciences ; Public, Environmental & Occupational Health
研究领域[WOS]Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
关键词[WOS]PULSE-WAVE VELOCITY ; IMPAIRED GLUCOSE-TOLERANCE ; TYPE-2 DIABETIC-PATIENTS ; PREDICTS CARDIOVASCULAR MORTALITY ; COHORT STUDY-CVD ; FASTING GLUCOSE ; METABOLIC SYNDROME ; VASCULAR FUNCTION ; RISK-FACTORS ; DIAGNOSIS
英文摘要

Objective To investigate the relationship between arterial stiffness and pre-diabetes when assessed by the new glycosylated hemoglobin A(1c) (HbA(1c)) 5.7%-6.4% criterion or by impaired fasting glucose in middle aged Chinese.

Methods 1122 adults aged 55 years or younger in the health examination centers for physical check-ups were enrolled in the two large-sized Tertiary Comprehensive Hospitals in Beijing from June 2011 to June 2012 after excluding those who previously had been diagnosed or treated as diabetes or cardiovascular disease. Subjects with a diagnosis of pre-diabetes according to impaired fasting glucose (IFG) (fasting plasma glucose (FPG) levels at 5.6-6.9 mmol/L), HbA(1c) levels at 5.7%-6.4%, or both, were classified into four groups for observation: (1) Normoglycaemia (HbA(1c)< 5.7% and FPG < 5.6 mmol/L); (2) IFG alone (FPG levels at 5.6-6.9 mmol/L and HbA(1c)< 5.7%); (3) HbA(1c) 5.7%-6.4% alone (HbA1c levels at 5.7%-6.4% and FPG < 5.6 mmol/L); and (4) both HbA(1c) 5.7%-6.4% and IFG (HbA(1c) levels at 5.7%-6.4% and FPG levels at 5.6-6.9 mmol/L). All subjects were measured for weight, height, waist circumference, blood pressure, fasting plasma glucose, HbA(1c), lipid profile and brachial-ankle pulse wave velocity (baPWV).

Results The mean values of baPWV were 1282 +/- 8, 1311 +/- 10, 1398 +/- 30, and 1418 +/- 27 cm/s (Mean +/- SE) in Normoglycaemia, HbA(1c) 5.7%-6.4% alone, IFG alone and the both HbA(1c) 5.7%-6.4% and IFG groups, respectively. After adjusting for age, gender, blood pressure, BMI and triglyceride, baPWV was significantly higher in subjects with both HbA(1c) 5.7%-6.4% and IFG compared among the subjects with Normoglycaemia (1350 +/- 14 vs. 1301 +/- 6 cm/s, P= 0.002) and HbA1c 5.7%-6.4% alone (1350 +/- 14 vs. 1309 +/- 8 cm/s, P= 0.013).

Conclusion Subjects with pre-diabetes exhibited a greater arterial stiffness.

语种英语
WOS记录号WOS:000324858400002
项目编号2008BAI52B03
资助机构National Science &amp ; Technology Pillar Program
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65566
专题北京大学公共卫生学院
医学人文研究院/公共教学部_哲学与社会科学系
作者单位1.Inst Aviat Med AF, Beijing 100142, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Shen Li,Zhang Yan Ge,Liu Min,et al. Increased Arterial Stiffness in Subjects with Pre-diabetes among Middle Aged Population in Beijing, China[J]. BIOMEDICAL AND ENVIRONMENTAL SCIENCES,2013,26(9):717-725.
APA Shen Li.,Zhang Yan Ge.,Liu Min.,Wu Liu Xin.,Qiang Dong Chang.,...&Jiang Yuan Yuan.(2013).Increased Arterial Stiffness in Subjects with Pre-diabetes among Middle Aged Population in Beijing, China.BIOMEDICAL AND ENVIRONMENTAL SCIENCES,26(9),717-725.
MLA Shen Li,et al."Increased Arterial Stiffness in Subjects with Pre-diabetes among Middle Aged Population in Beijing, China".BIOMEDICAL AND ENVIRONMENTAL SCIENCES 26.9(2013):717-725.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Shen Li]的文章
[Zhang Yan Ge]的文章
[Liu Min]的文章
百度学术
百度学术中相似的文章
[Shen Li]的文章
[Zhang Yan Ge]的文章
[Liu Min]的文章
必应学术
必应学术中相似的文章
[Shen Li]的文章
[Zhang Yan Ge]的文章
[Liu Min]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。