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学科主题临床医学
Contrasting clinical outcomes between different modes of peritoneal dialysis regimens: Two center experiences in China
Chen, W.1; Gu, Y.1; Han, Q-F1; Wang, T.1,2
关键词dialysis ultrafiltration fluid removal volume status
刊名KIDNEY INTERNATIONAL
2008-04-01
DOI10.1038/sj.ki.5002602
suppl.108页:S56-S62
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Urology & Nephrology
研究领域[WOS]Urology & Nephrology
关键词[WOS]RESIDUAL RENAL-FUNCTION ; LEFT-VENTRICULAR HYPERTROPHY ; CAPD PATIENTS ; NUTRITIONAL-STATUS ; CONTROLLED-TRIAL ; MORTALITY-RATES ; FLUID STATUS ; HEMODIALYSIS ; ASSOCIATION ; TRANSPORT
英文摘要

In the present study, we compared the clinical outcomes between two different modes of peritoneal dialysis (PD) and explored the possible role of volume overload in continuous ambulatory peritoneal dialysis (CAPD) patients. A longitudinal and a cross-sectional study were included. Patients received either an ′adaptative ultrafiltration (UF)′ PD regimen, which focused on gradually increasing peritoneal ultrafiltration (PDi group), or traditional PD treatment (PDt group). Patients′ demographic characteristics, nutritional status, fluid removal as well as fluid status were recorded. In the cross-sectional study, all clinically stable patients who were treated with CAPD for at least three months were enrolled and grouped according to their time on dialysis: short term, medium term, and long term. Both studies showed that PDi and PDt patients had distinct fluid removal patterns. PDt patients had decreased total fluid removal with worsening fluid status and deteriorating nutritional status, whereas PDi patients remained rather stable in relation to fluid removal, fluid status, and improving nutritional status. Cox regression analysis confirmed that the PDi group had better patient survival than the PDt group. Our data suggest that traditional and ′adaptative UF′ PD therapy may have distinct fluid removal patterns over time on dialysis, and this unique pattern might partly explain the still unacceptable high mortality of long-term CAPD patients.

语种英语
WOS记录号WOS:000254559100008
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65575
专题北京大学第三临床医学院_肾内科
作者单位1.Peking Univ, Third Hosp, Div Nephrol, Beijing 100083, Peoples R China
2.Peking Univ, First Hosp, Div Nephrol, Beijing 100083, Peoples R China
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Chen, W.,Gu, Y.,Han, Q-F,et al. Contrasting clinical outcomes between different modes of peritoneal dialysis regimens: Two center experiences in China[J]. KIDNEY INTERNATIONAL,2008,suppl.108:S56-S62.
APA Chen, W.,Gu, Y.,Han, Q-F,&Wang, T..(2008).Contrasting clinical outcomes between different modes of peritoneal dialysis regimens: Two center experiences in China.KIDNEY INTERNATIONAL,suppl.108,S56-S62.
MLA Chen, W.,et al."Contrasting clinical outcomes between different modes of peritoneal dialysis regimens: Two center experiences in China".KIDNEY INTERNATIONAL suppl.108(2008):S56-S62.
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