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学科主题: 临床医学
题名:
A Study to Draw a Normative Database of Laryngopharynx pH Profile in Chinese
作者: Feng, Guijian1; Wang, Junyao1; Zhang, Lihong2; Liu, Yulan1
关键词: Esophageal pH monitoring ; Gastroesophageal reflux ; Laryngopharyngeal reflux
刊名: JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY
发表日期: 2014-07-01
DOI: 10.5056/jnm13138
卷: 20, 期:3, 页:347-351
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology ; Clinical Neurology
研究领域[WOS]: Gastroenterology & Hepatology ; Neurosciences & Neurology
关键词[WOS]: GASTROESOPHAGEAL-REFLUX DISEASE ; GASTRIC-MUCOSAL PATCH ; CLINICAL SPECTRUM ; PREVALENCE ; POPULATION ; RELIABILITY ; SYMPTOMS ; VALIDITY
英文摘要:

Background/Aims

To draw a normative database of laryngopharynx pH profile in Chinese subjects.

Methods

Normal volunteers were recruited from "www.Ganji.com" and People′s hospital between May 2008 and December 2009. The Restech pH Probes were calibrated in pH 7 and pH 4 buffer solutions according to the manufacturer′s instructions. Each volunteer was asked to wear the device for a 24-hour period and was encouraged to participate in normal daily activities.

Results

The healthy volunteers consisted of 20 males and 9 females with a median age of 23 years (interquartile range, 21 to 32 years). The 95th percentiles for % total times at pH < 4, pH < 4.5, pH < 5.0 and pH < 5.5 for the oropharynx pH catheter were 0.06%, 1.01%, 7.23% and 27.34%, respectively. The 95th percentile for number of reflux events within the 24-hour period at pH < 4, pH < 4.5, pH < 5.0 and pH < 5.5 were 2.0, 18.0, 107.5 and 284.5, respectively.

Conclusions

This is the first study to systematically assess the degree of reflux detected by the new pH probe in healthy asymptomatic Chinese volunteers and to report normative values in Chinese people. Using an oropharyngeal pH catheter to monitor laryngopharyngeal reflux indicated that in healthy Chinese, reflux should be considered normal if the percent time at pH less than 4.5 is no more than 1%.

语种: 英语
项目资助者: Respiratory Technology Corporation
WOS记录号: WOS:000338614700008
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65592
Appears in Collections:北京大学第二临床医学院_消化内科_期刊论文

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作者单位: 1.Peking Univ, Dept Gastroenterol, Peoples Hosp, Beijing 100044, Peoples R China
2.Peking Univ, Dept Otorhinolaryngol, Peoples Hosp, Beijing 100044, Peoples R China

Recommended Citation:
Feng, Guijian,Wang, Junyao,Zhang, Lihong,et al. A Study to Draw a Normative Database of Laryngopharynx pH Profile in Chinese[J]. JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY,2014,20(3):347-351.
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