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学科主题: 临床医学
题名:
Rationale, Design, and Baseline Characteristics of the EPICOR Asia Study (Long-tErm follow-uP of antithrombotic management patterns In Acute CORonary Syndrome patients in Asia)
作者: Huo, Yong1; Lee, Stephen W. -L.2; Sawhney, Jitendra P. S.3; Kim, Hyo-Soo4; Krittayaphong, Rungroj5; Nhan, Vo T.6; Alonso-Garcia, Angeles7; Han, Ya Ling8; Ge, Junbo9; Chin, Chee Tang10,11; Ong, Tiong K.12; Jan, Stephen13; Itoh, Yohji14; Vega, Ana Maria15; Pocock, Stuart16
刊名: CLINICAL CARDIOLOGY
发表日期: 2015-09-01
DOI: 10.1002/clc.22431
卷: 38, 期:9, 页:511-519
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Cardiac & Cardiovascular Systems
研究领域[WOS]: Cardiovascular System & Cardiology
关键词[WOS]: ST-SEGMENT ELEVATION ; ACUTE MYOCARDIAL-INFARCTION ; ASSOCIATION TASK-FORCE ; BLEEDING COMPLICATIONS ; ATRIAL-FIBRILLATION ; PRACTICE GUIDELINES ; SYNDROME REGISTRY ; CLOPIDOGREL ; THERAPY ; INTERVENTION
英文摘要:

BackgroundIn-hospital and postdischarge mortality for acute coronary syndromes (ACS) vary across Asia and remain generally poorer than globally. The relationship between real-life antithrombotic management patterns (AMPs) and ACS-related outcomes in Asia is unclear.

MethodsEPICOR Asia (Long-tErm follow-uP of antithrombotic management patterns In acute CORonary syndrome patients in Asia) (NCT01361386) is a prospective, multinational, observational study of patients discharged after hospitalization for an ACS, with 2-year follow-up. The aim is to describe short- and long-term (up to 2 years post-index event) AMPs in patients hospitalized for ACS and to record clinical outcomes, healthcare resource use, and self-reported health status. Pre- and in-hospital management, AMPs, and associated outcomes, with particular focus on ischemic and bleeding events, will be recorded during the 2-year follow up.

ResultsBetween June 2011 and May 2012, 13 005 patients were enrolled. From these, 12 922 patients surviving an ACS (6616 with STEMI, 2570 with NSTEMI, and 3736 with UA) were eligible for inclusion from 219 hospitals across 8 countries and regions in Asia: China (n = 8214), Hong Kong (n = 177), India (n = 2468), Malaysia (n = 100), Singapore (n = 93), South Korea (n = 705), Thailand (n = 957), and Vietnam (n = 208).

ConclusionsEPICOR Asia will provide information regarding clinical management and AMPs for ACS patients in Asia. Impact of AMPs on clinical outcomes, healthcare resource use, and self-reported health status both during hospitalization and up to 2 years after discharge will also be described.

语种: 英语
项目资助者: AstraZeneca ; Servier ; Sanofi ; Salubris Pharmaceutical Co. Ltd. ; Yi Sheng Pharmaceutical Co. Ltd. ; Shandong Huaan Pharmaceutical Co. Ltd. ; MicroPort Corporation ; Abbott Laboratories ; Eli Lilly ; Roche ; Boston Scientific
WOS记录号: WOS:000362093000001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65596
Appears in Collections:北京大学第一临床医学院_心血管内科_期刊论文

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作者单位: 1.Shenyang Northern Hosp, Dept Cardiol, Shenyang, Peoples R China
2.Zhongshan Hosp, Dept Cardiol, Shanghai, Peoples R China
3.Natl Heart Ctr Singapore, Dept Cardiol, Singapore, Singapore
4.Duke NUS Grad Med Sch, Singapore, Singapore
5.Sarawak Gen Hosp, Dept Cardiol, Kuching, Malaysia
6.AstraZeneca, Div Clin Sci, Osaka, Japan
7.AstraZeneca, Global Med Affairs, Observat Res Ctr, Madrid, Spain
8.Peking Univ, Hosp 1, Dept Cardiol, Beijing 100034, Peoples R China
9.Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
10.Seoul Natl Univ Hosp, Clin Res Inst, Seoul 110744, South Korea
11.Mahidol Univ, Siriraj Hosp, Dept Med, Bangkok 10700, Thailand
12.St Georges Univ London, Cardiovasc Sci Res Ctr, London, England
13.Univ Sydney, Hlth Econ Program, George Inst Global Hlth, Sydney, NSW 2006, Australia
14.London Sch Hyg & Trop Med, Dept Med Stat, London WC1, England
15.Sir Ganga Ram Hosp, Dept Cardiol, New Delhi, India
16.Cho Ray Hosp, Dept Med, Ho Chi Minh City, Vietnam

Recommended Citation:
Huo, Yong,Lee, Stephen W. -L.,Sawhney, Jitendra P. S.,et al. Rationale, Design, and Baseline Characteristics of the EPICOR Asia Study (Long-tErm follow-uP of antithrombotic management patterns In Acute CORonary Syndrome patients in Asia)[J]. CLINICAL CARDIOLOGY,2015,38(9):511-519.
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