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学科主题: 临床医学
题名:
The High Prevalence of Knee Osteoarthritis in a Rural Chinese Population: The Wuchuan Osteoarthritis Study
作者: Kang, Xiaozheng; Fransen, Marlene2; Zhang, Yuqing3; Li, Hu; Ke, Yan; Lu, Ming; Su, Steve2; Song, Xiongying4; Guo, Yong; Chen, Jie; Niu, Jingbo3; Felson, David3; Lin, Jianhao1
刊名: ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
发表日期: 2009-05-15
DOI: 10.1002/art.24464
卷: 61, 期:5, 页:641-647
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Rheumatology
研究领域[WOS]: Rheumatology
关键词[WOS]: WHO-ILAR COPCORD ; MUSCULOSKELETAL PAIN ; EPIDEMIOLOGY
英文摘要:

Objective. To estimate the prevalence of radiographic and symptomatic knee osteoarthritis (OA) in a remote rural region of northern China, and compare them with those reported in Beijing and with data from the Framingham (Massachusetts) cohort.

Methods. A population-based cross-Sectional survey was conducted among 1,030 residents of Wuchuan County, Inner Mongolia, age >= 50 years. Survey participants, mostly farmers reporting heavy physical occupational activity, completed an interviewer-based questionnaire, and bilateral weight-bearing posteroanterior semiflexed knee radiographs were obtained.

Results. Whereas the overall prevalence of radiographic knee OA was similar to that demonstrated in the Beijing OA study, men in Wuchuan had approximately double the prevalence of severe radiographic: knee OA (prevalence ratio [PR] 2.5, 95% confidence interval [95% CI] 1.6-3.8) and symptomatic knee OA (PR 1.9, 95%, CI 1.3-2.9). Women in Wuchuan also had a higher prevalence of both severe radiographic (PR 1.4, 95% CI 1.0-2.0) and symptomatic knee OA (PR 1.6, 95′% CI 1.2-2.1) compared with their Beijing counterparts. The prevalence of bilateral OA and lateral compartment disease were 2-3 times higher in both Chinese cohorts compared with estimates from the Framingham OA study.

Conclusion. The prevalence of symptomatic knee OA in rural areas of China is much higher than reported from urban regions of China or in the Framingham cohort. The higher representation of bilateral and lateral compartment disease in China suggests a unique phenotype to OA. These findings will be useful for guiding the distribution of future health care resources and preventive strategies.

语种: 英语
所属项目编号: AR-47785
项目资助者: China National 211 Project ; Wu Jieping Medical Foundation of China ; National Health and Medical Research Council (Australia) ; NIH
WOS记录号: WOS:000265949700013
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65684
Appears in Collections:北京大学第二临床医学院_期刊论文

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作者单位: 1.Peking Univ, Peoples Hosp, Arthrit Inst, Beijing 100044, Peoples R China
2.George Inst Int Hlth, Sydney, NSW, Australia
3.Boston Univ, Sch Med, Boston, MA 02118 USA
4.Changxindian Hosp, Fengtai, Peoples R China

Recommended Citation:
Kang, Xiaozheng,Fransen, Marlene,Zhang, Yuqing,et al. The High Prevalence of Knee Osteoarthritis in a Rural Chinese Population: The Wuchuan Osteoarthritis Study[J]. ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH,2009,61(5):641-647.
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