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学科主题: 临床医学
题名:
Prevalence of chronic kidney disease in a middle and old-aged population of Beijing
作者: Li, ZY; Xu, GB; Xia, TA; Wang, HY
关键词: chronic kidney disease ; prevalence ; middle and old-aged population ; epidemiology
刊名: CLINICA CHIMICA ACTA
发表日期: 2006-04-01
DOI: 10.1016/j.cca.2005.10.011
卷: 366, 期:1-2, 页:209-215
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medical Laboratory Technology
研究领域[WOS]: Medical Laboratory Technology
英文摘要:

Background: Chronic kidney disease (CKD) was epidemic worldwide. The prevalence of CKD indicators, including proteinuria, hematuria/uninfectious leukocyturia and reduced GFR, was investigated in the middle and old-aged population of Beijing Shijingshan district.

Methods: Subjects of 2310 aged >= 40 y were enrolled. Their health conditions were taken by questionnaires and physical check-ups. Spot urine albumin to creatinine ratio, spot urine dipstick and microscopy for urine red cell and leukocyte, and serum creatinine was determined. Using simplified Modification of Diet in Renal Disease Study equation estimated GFR assessed renal function. The associations between age, gender, diabetes mellitus, and hypertension, and indicators of kidney damage were examined.

Results: Through the questionnaires, the history of diabetes mellitus, hypertension and CKD were found in 28%, 47.1% and 3.6% of subjects, respectively. Albuminuria was detected in 8.4% of subjects, hematuria and uninfectious leukocyturia in 0.7%, and reduced GFR in 4.9%. Approximately 12.9% had at least I indicator of CKD. The known rate of CKD in the studied Population was 7.1%. Age, diabetes mellitus, hyper fasting blood glucose and hypertension were independently associated with albuminuria; age, gender, hyper uric acid and albuminuria with reduced GFR. When proteinuria and reduced GFR were determined Using Spot urine dipstick protein >= 25 mg/dl and serum creatinine >= 133 mu mol/l, the prevalence of proteinuria and reduced GFR were 4.7% and 0.8%, respectively.

Conclusion: The prevalence of CKD is common in middle and old-aged population of Beijing, especially in the elderly, but the known rate was relatively low. These findings highlight the clinical and public health importance of CKD. (c) 2005 Elsevier B.V. All rights reserved.

语种: 英语
WOS记录号: WOS:000236378200024
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65714
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.Peking Univ, Hosp 1, Dept Clin Lab, Beijing 100034, Peoples R China
2.Peking Univ, Hosp 1, Inst Nephrol, Beijing 100034, Peoples R China
3.Peking Univ, Hosp 1, Div Nephrol, Beijing 100034, Peoples R China

Recommended Citation:
Li, ZY,Xu, GB,Xia, TA,et al. Prevalence of chronic kidney disease in a middle and old-aged population of Beijing[J]. CLINICA CHIMICA ACTA,2006,366(1-2):209-215.
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