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学科主题临床医学
Overview of lupus nephritis management guidelines and perspective from Asia
Mok, Chi Chiu1; Yap, Desmond Y. H.2; Navarra, Sandra V.3; Liu, Zhi-Hong4; Zhao, Ming-Hui5; Lu, Liangjing6; Takeuchi, Tsutomu7; Avihingsanon, Yingyos8; Yu, Xue-Qing9; Lapid, Elizabeth A.3; Lugue-Lizardo, Lenrore R.3; Sumethkul, Vasant10; Shen, Nan6; Chen, Shun-Le6; Chan, Tak Mao2; ALNN
关键词Asia lupus nephritis
刊名NEPHROLOGY
2014
DOI10.1111/nep.12136
19期:1页:11-20
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Urology & Nephrology
研究领域[WOS]Urology & Nephrology
关键词[WOS]COATED MYCOPHENOLATE SODIUM ; RANDOMIZED CONTROLLED-TRIAL ; LONG-TERM ; INTRAVENOUS CYCLOPHOSPHAMIDE ; ORAL CYCLOPHOSPHAMIDE ; INDUCTION TREATMENT ; PULSE METHYLPREDNISOLONE ; ANGIOTENSIN INHIBITION ; MAINTENANCE THERAPY ; MOFETIL
英文摘要

Lupus nephritis (LN) is a common and important manifestation of systemic lupus erythematosus (SLE). Evidence suggests higher rates of lupus renal involvement in Asian populations, and maybe more severe nephritis, compared with other racial or ethnic groups. The management of LN has evolved considerably over the past three decades, based on observations from clinical studies that investigated different immunosuppressive agents including corticosteroids, cyclophosphamide, azathioprine, mycophenolic acid, calcineurin inhibitors and novel biologic therapies. This is accompanied by improvements in both the short-term treatment response rate and long-term renal function preservation. Treatment guidelines for LN have recently been issued by rheumatology and nephrology communities in U.S.A. and Europe. In view of the racial difference in disease manifestation and response to therapy, and the substantial disease burden in Asia, a panel of 15 nephrologists and rheumatologists from different Asian regions with extensive experience in lupus nephritis - the Steering Group for the Asian Lupus Nephritis Network (ALNN) - met and discussed the management of lupus nephritis in Asian patients. The group has also reviewed and deliberated on the recently published recommendations from other parts of the world. This manuscript summarizes the discussions by the group and presents consensus views on the clinical management and treatment of adult Asian patients with LN, taking into account both the available evidence and expert opinion in areas where evidence remains to be sought.

语种英语
WOS记录号WOS:000328573500003
资助机构Wai Hung Charitable Foundation, Mr G. King ; Estate of the late Mr Chan Wing Hei ; Astellas Pharma Co. Hong Kong Ltd. ; Roche Hong Kong Ltd. ; Endowment Fund established for the &prime ; Yu Chiu Kwong Professorship in Medicine&prime ; at The University of Hong Kong
引用统计
被引频次:19[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65726
专题北京大学第一临床医学院_肾脏内科
作者单位1.Renji Hosp, Dept Rheumatol, Shanghai, Peoples R China
2.Keio Univ, Sch Med, Div Rheumatol, Tokyo 108, Japan
3.Mahidol Univ, Div Nephrol, Bangkok 10700, Thailand
4.Jinling Hosp, Res Inst Nephrol, Nanjing, Peoples R China
5.Beijing Univ, Hosp 1, Renal Div, Beijing 100871, Peoples R China
6.Tuen Mun Hosp, Dept Med & Geriatr, Div Rheumatol, Hong Kong, Hong Kong, Peoples R China
7.Univ Hong Kong, Dept Med, Div Nephrol, Hong Kong, Hong Kong, Peoples R China
8.Univ Santo Tomas, St Lukes Med Ctr, Rheumatol Div, Manila, Philippines
9.Chulalongkorn Univ, Dept Med, Renal Div, Bangkok 10330, Thailand
10.Sun Yat Sen Univ, Hosp 1, Dept Nephrol, Guangzhou, Peoples R China
推荐引用方式
GB/T 7714
Mok, Chi Chiu,Yap, Desmond Y. H.,Navarra, Sandra V.,et al. Overview of lupus nephritis management guidelines and perspective from Asia[J]. NEPHROLOGY,2014,19(1):11-20.
APA Mok, Chi Chiu.,Yap, Desmond Y. H..,Navarra, Sandra V..,Liu, Zhi-Hong.,Zhao, Ming-Hui.,...&ALNN.(2014).Overview of lupus nephritis management guidelines and perspective from Asia.NEPHROLOGY,19(1),11-20.
MLA Mok, Chi Chiu,et al."Overview of lupus nephritis management guidelines and perspective from Asia".NEPHROLOGY 19.1(2014):11-20.
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