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学科主题临床医学
Avascular necrosis of bone in severe acute respiratory syndrome
Hong, N; Du, XK
关键词bones necrosis magnetic resonance steroids
刊名CLINICAL RADIOLOGY
2004-07-01
DOI10.1016/j.crad.2003.12.008
59期:7页:602-608
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]STEROID-INDUCED OSTEONECROSIS ; RENAL-TRANSPLANTATION ; FEMORAL-HEAD ; CORONAVIRUS ; RISK ; MRI
英文摘要

AIM: To report the incidence of avascular osteonecrosis (AVN) in severe acute respiratory syndrome (SARS) patients.

MATERIALS AND METHODS: Sixty-seven SARS patients who had Large joint pain between March 2003 and May 2003 underwent both plain radiographs and magnetic resonance imaging (MRI) examination on the same day. ALL patients received steroids and ribavirin treatment. All plain radiographs and MR images were analysed by two experienced musculoskeletal radiologists. Any abnormalities, location, extent, morphology, the number, size and signal intensity of lesions were evaluated.

RESULTS: Twenty-eight patients were identified with AVN, The mean time to diagnosis of AVN was 119 days after the onset of SARS, or 116 days after steroid use. Three patients had early bilateral AVN of the femoral, head, four patients of one femoral head, five patients of the bilateral hips and knees, four patients of the ipsilateral hip and knees, 10 patients of the knee(s), one patient of the right proximal fibula, and one patient of the knees and talus. Results of hip, knee and ankle plain radiographs were negative.

CONCLUSION: AVN can occur in the patients with SARS. AVN had a strong association with steroid use. More studies are required to confirm whether the virus itself can also lead to AVN. (C) 2004 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000222341800007
引用统计
被引频次:45[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65797
专题北京大学第二临床医学院_放射科
作者单位Peking Univ, Dept Radiol, Peoples Hosp, Beijing 100044, Peoples R China
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Hong, N,Du, XK. Avascular necrosis of bone in severe acute respiratory syndrome[J]. CLINICAL RADIOLOGY,2004,59(7):602-608.
APA Hong, N,&Du, XK.(2004).Avascular necrosis of bone in severe acute respiratory syndrome.CLINICAL RADIOLOGY,59(7),602-608.
MLA Hong, N,et al."Avascular necrosis of bone in severe acute respiratory syndrome".CLINICAL RADIOLOGY 59.7(2004):602-608.
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