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学科主题: 临床医学
题名:
Contrast-Enhanced Sonography for Quantitative Assessment of Portal Hypertension in Patients With Liver Cirrhosis
作者: Qu, En-Ze1; Zhang, Ying-Cai2; Li, Zhi-Yan3; Liu, Yang3; Wang, Jin-Rui4
关键词: contrast-enhanced sonography ; gastrointestinal ultrasound ; noninvasive ; portal hypertension
刊名: JOURNAL OF ULTRASOUND IN MEDICINE
发表日期: 2014-11-01
DOI: 10.7863/ultra.33.11.1971
卷: 33, 期:11, 页:1971-1977
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: ARTERIAL BUFFER RESPONSE ; HEPATIC PERFUSION ; DYNAMIC CT ; BLOOD-FLOW ; PRESSURE ; COMPLICATIONS ; PARAMETERS ; SEVERITY ; DISEASE ; US
英文摘要:

Objectives The clinical utility of contrast-enhanced sonography in portal hypertension remains unclear. We explored the feasibility of using contrast-enhanced sonography for noninvasive assessment of portal venous pressure.

Methods Twenty healthy individuals (control group; 9 men; mean age, 46.4 years) and 18 patients with portal hypertension (is men; mean age, 46.2 years) were enrolled in this study. The portal hypertension group included patients who underwent splenectomy and pericardial blood vessel disarticulation at our hospital from October 2010 to March 2011. One week before surgery, patients with portal hypertension underwent preoperative liver contrast-enhanced sonography. Two-dimensional, Doppler, and contrast-enhanced sonographic parameters were compared between the groups. Portal venous pressure was measured intraoperatively by portal vein puncture in the portal hypertension group, and its relationship with the other parameters was analyzed.

Results The 2-dimensional, Doppler, and contrast-enhanced sonographic parameters differed between the groups (P<.01). Portal venous pressure was inversely correlated with the area under the portal vein/hepatic artery time-intensity curve ratio (Qp/Qa), portal vein/hepatic artery strength ratio (Ip/Ia), and portal vein/hepatic artery wash-in perfusion slope ratio (beta p/beta a), with correlation coefficients of -0.701, -0.625, and -0.494, respectively.

Conclusions Measurement of the liver contrast-enhanced sonographic parameters Qp/Qa, Ip/Ia, and beta p/beta a could be used as a new quantitative method for noninvasively assessing portal venous pressure.

语种: 英语
所属项目编号: 20090001110092
项目资助者: Doctoral Foundation of the Chinese Ministry of Education
WOS记录号: WOS:000343794400011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65823
Appears in Collections:北京大学第三临床医学院_超声诊断科_期刊论文

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作者单位: 1.Sun Yat Sen Univ, Affiliated Hosp 3, Dept Ultrasound, Guangzhou 510275, Guangdong, Peoples R China
2.Sun Yat Sen Univ, Affiliated Hosp 3, Dept Liver Transplantat, Guangzhou 510275, Guangdong, Peoples R China
3.302 Mil Hosp China, Dept Ultrasound, Beijing, Peoples R China
4.Peking Univ, Hosp 3, Dept Ultrasound, Beijing 100191, Peoples R China

Recommended Citation:
Qu, En-Ze,Zhang, Ying-Cai,Li, Zhi-Yan,et al. Contrast-Enhanced Sonography for Quantitative Assessment of Portal Hypertension in Patients With Liver Cirrhosis[J]. JOURNAL OF ULTRASOUND IN MEDICINE,2014,33(11):1971-1977.
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