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学科主题: 临床医学
题名:
Global efforts in conquering lung cancer in China
作者: Yan, Li1,2; Xu, Li3
关键词: Lung cancer ; Targeted agents ; Biomarker ; Personalized medicine ; Healthcare in China
刊名: CHINESE JOURNAL OF CANCER
发表日期: 2015-07-28
DOI: 10.1186/s40880-015-0034-6
卷: 34, 页:1-3
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Oncology
研究领域[WOS]: Oncology
关键词[WOS]: AIR-POLLUTION ; CRIZOTINIB ; GEFITINIB ; 1ST-LINE
英文摘要:

Lung cancer, the most prevalent and deadly malignancy in the world, poses a particularly critical healthcare challenge to China due to the rapidly increasing new cases and the unique cancer genetics in Chinese patient population. Substantial progress has been made in molecular diagnosis and personalized treatment of the disease. The field is now moving towards multiple new directions to include (1) new generation of targeted agents such as epidermal growth factor receptor and anaplastic lymphoma kinase inhibitors to overcome resistance to their early generation counterparts; and (2) deeper understanding of tumor genetics of each individual patient and consequently the application of biomarkers to guide personalized treatment as well as novel drug development including combination therapy. The increasing capacity in innovative cancer drug research and development is supported by extensive collaboration within China and globally, and across academia and industry, to build up expertise and infrastructure in early-phase clinical testing of novel drugs. With these combined efforts, new and better medicines will be available for lung cancer patients in China in the near future.

语种: 英语
WOS记录号: WOS:000360228200001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65827
Appears in Collections:北京大学临床肿瘤学院_期刊论文

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作者单位: 1.US Chinese Anticanc Assoc, Martinez, CA 94553 USA
2.Jiangsu Hengrui Med Co LTD, Shanghai 200122, Peoples R China
3.Peking Univ, Sch Oncol, Beijing Canc Hosp & Inst, Beijing 100142, Peoples R China

Recommended Citation:
Yan, Li,Xu, Li. Global efforts in conquering lung cancer in China[J]. CHINESE JOURNAL OF CANCER,2015,34:1-3.
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