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学科主题: 临床医学
题名:
The Effects of Needling Fenglong (ST40) and Neiguan (PC6) on IL-17 of ApoE-Gene-Knockout Mice′s Liver
作者: Lee, Fu Yun1; Huo, Ze Jun2; Zhang, Li1; Guo, Jia2; Chen, Huan1; Liu, Tong1; Peng, Bo1; Hong, Pei Xin1; Peng, Yuan Yuan1; Fan, Yi Fan1; Chen, Yu Pei1
刊名: EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
发表日期: 2014
DOI: 10.1155/2014/691863
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Integrative & Complementary Medicine
研究领域[WOS]: Integrative & Complementary Medicine
关键词[WOS]: LOOP
英文摘要:

The aim of the present paper was to observe the effects of needling ST40 and PC6 on IL-17 of ApoE(-/-) mice with fatty liver. Forty male ApoE(-/-) mice were randomized into Needling-Acupoint Group, Simvastatin Intragastric Administration Group, Needling Nonacupoint Group, and Model Group. Each was fed with high fat diet for 8 weeks since 16 weeks of age; after 8 weeks of intervention, mice were sacrificed and tested for various examinations. Result showed that the body weight, TC, and serum IL-17 in Needling-Acupoint Group decreased. Compared with Model Group, the immunohistochemical expressions of IL-17 in liver tissue were significantly decreased among the other three groups. In conclusion, acupuncture was able to lower the expression of IL-17 level both in serum and liver tissue in ApoE(-/-) mice, which is helpful to reduce the inflammation and defers the progress from fatty liver to cirrhosis.

语种: 英语
WOS记录号: WOS:000333638100001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65872
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: 1.Beijing Univ Chinese Med, Sch Acupuncture & Moxibust, Beijing 100029, Peoples R China
2.Peking Univ, Acupuncture & Moxibust Dept, Hosp 3, Beijing 100191, Peoples R China

Recommended Citation:
Lee, Fu Yun,Huo, Ze Jun,Zhang, Li,et al. The Effects of Needling Fenglong (ST40) and Neiguan (PC6) on IL-17 of ApoE-Gene-Knockout Mice′s Liver[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2014.
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