IR@PKUHSC  > 北京大学第三临床医学院
学科主题临床医学
The Effects of Needling Fenglong (ST40) and Neiguan (PC6) on IL-17 of ApoE-Gene-Knockout Mice′s Liver
Lee, Fu Yun1; Huo, Ze Jun2; Zhang, Li1; Guo, Jia2; Chen, Huan1; Liu, Tong1; Peng, Bo1; Hong, Pei Xin1; Peng, Yuan Yuan1; Fan, Yi Fan1; Chen, Yu Pei1
刊名EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
2014
DOI10.1155/2014/691863
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Integrative & Complementary Medicine
研究领域[WOS]Integrative & Complementary Medicine
关键词[WOS]LOOP
英文摘要

The aim of the present paper was to observe the effects of needling ST40 and PC6 on IL-17 of ApoE(-/-) mice with fatty liver. Forty male ApoE(-/-) mice were randomized into Needling-Acupoint Group, Simvastatin Intragastric Administration Group, Needling Nonacupoint Group, and Model Group. Each was fed with high fat diet for 8 weeks since 16 weeks of age; after 8 weeks of intervention, mice were sacrificed and tested for various examinations. Result showed that the body weight, TC, and serum IL-17 in Needling-Acupoint Group decreased. Compared with Model Group, the immunohistochemical expressions of IL-17 in liver tissue were significantly decreased among the other three groups. In conclusion, acupuncture was able to lower the expression of IL-17 level both in serum and liver tissue in ApoE(-/-) mice, which is helpful to reduce the inflammation and defers the progress from fatty liver to cirrhosis.

语种英语
WOS记录号WOS:000333638100001
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65872
专题北京大学第三临床医学院
作者单位1.Beijing Univ Chinese Med, Sch Acupuncture & Moxibust, Beijing 100029, Peoples R China
2.Peking Univ, Acupuncture & Moxibust Dept, Hosp 3, Beijing 100191, Peoples R China
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GB/T 7714
Lee, Fu Yun,Huo, Ze Jun,Zhang, Li,et al. The Effects of Needling Fenglong (ST40) and Neiguan (PC6) on IL-17 of ApoE-Gene-Knockout Mice′s Liver[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2014.
APA Lee, Fu Yun.,Huo, Ze Jun.,Zhang, Li.,Guo, Jia.,Chen, Huan.,...&Chen, Yu Pei.(2014).The Effects of Needling Fenglong (ST40) and Neiguan (PC6) on IL-17 of ApoE-Gene-Knockout Mice′s Liver.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE.
MLA Lee, Fu Yun,et al."The Effects of Needling Fenglong (ST40) and Neiguan (PC6) on IL-17 of ApoE-Gene-Knockout Mice′s Liver".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2014).
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