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学科主题临床医学
Results of Cervical Recapping Laminoplasty: Gross Anatomical Changes, Biomechanical Evaluation at Different Time Points and Degrees of Level Involvement
Si, Yu1; Wang, Zhenyu1; Yu, Tao1; Lin, Guo Zhong1; Zhang, Jia1; Zhang, Kuo2; Zhang, Hua3; Li, Yuan Chao4
刊名PLOS ONE
2014-06-20
DOI10.1371/journal.pone.0100689
9期:6
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Multidisciplinary Sciences
研究领域[WOS]Science & Technology - Other Topics
关键词[WOS]OPEN-DOOR LAMINOPLASTY ; SPINAL-CORD TUMORS ; BILATERAL LAMINOTOMY ; LUMBAR SPINE ; IN-VITRO ; LAMINECTOMY ; MYELOPATHY ; DEFORMITY ; MODEL ; FLEXIBILITY
英文摘要

Background: Recapping laminoplasty has become the frequently-used approach to the spinal canal when bone decompression of the vertebral canal is not the goal. However, what changes will occur after surgery, and whether recapping laminoplasty can actually reduce the risk of delayed deformities remains unknown.

Methodology: We designed an animal experiment using a caprine model, and partitioned the animals into in vitro and in vivo surgical groups. We performed recapping laminoplasty on one group and laminectomy on another group. These animals were sacrificed six months after operating, cervical spines removed, biomechanically tested, and these data were compared to determine whether the recapping laminoplasty technique leads to subsequent differences in range of motion. Image data were also obtained before the surgery and when the animals were killed. Besides, we investigated the initial differences in kinetics between recapping laminoplasty and laminectomy. We did this by comparing data obtained from biomechanical testing of in vitro-performed recapping laminoplasty and laminectomy. Finally, we investigated the effect that longitudinal distance has on cervical mechanics. This was determined by performing a two-level recapping laminoplasty, and then extending the laminoplasty to the next level and repeating the mechanical testing at each step.

Principal Findings: There were three mainly morphological changes at the six months after laminoplasty: volume reduction and bone nonunion of the recapping laminae, irregular fibrosis formation around the facet joints and re-implanted lamina-ligamentous complex. In the biomechanical test, comparing with laminectomy, recapping laminoplasty didn′t show significant differences in the immediate postoperative comparison, while recapping laminoplasty demonstrated significantly decreased motion in flexion/extension six months later. Inclusion of additional levels in the laminotomy procedure didn′t lead to changes in immediate biomechanics.

Conclusions: Recapping laminoplasty can′t fully restore the posterior structure, but still reduced the risk of delayed cervical instability in a caprine model.

语种英语
WOS记录号WOS:000338276300108
项目编号5443002
资助机构National Natural Science Foundation of China
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65885
专题北京大学第三临床医学院_神经外科
北京大学医学部管理机构_医学部
北京大学医学部管理机构_北京大学医学部校医院
北京大学口腔医学院_第一门诊部
作者单位1.Peking Univ, Hosp 3, Dept Neurosurg, Beijing 100871, Peoples R China
2.Peking Univ, Hosp 3, Clin Epidemiol Res Ctr, Beijing 100871, Peoples R China
3.Shanghai Jiao Tong Univ, Sch Mech Engn, Shanghai 200030, Peoples R China
4.Dept Lab Anim Sci, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Si, Yu,Wang, Zhenyu,Yu, Tao,et al. Results of Cervical Recapping Laminoplasty: Gross Anatomical Changes, Biomechanical Evaluation at Different Time Points and Degrees of Level Involvement[J]. PLOS ONE,2014,9(6).
APA Si, Yu.,Wang, Zhenyu.,Yu, Tao.,Lin, Guo Zhong.,Zhang, Jia.,...&Li, Yuan Chao.(2014).Results of Cervical Recapping Laminoplasty: Gross Anatomical Changes, Biomechanical Evaluation at Different Time Points and Degrees of Level Involvement.PLOS ONE,9(6).
MLA Si, Yu,et al."Results of Cervical Recapping Laminoplasty: Gross Anatomical Changes, Biomechanical Evaluation at Different Time Points and Degrees of Level Involvement".PLOS ONE 9.6(2014).
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