|Results of Cervical Recapping Laminoplasty: Gross Anatomical Changes, Biomechanical Evaluation at Different Time Points and Degrees of Level Involvement|
|Si, Yu1; Wang, Zhenyu1; Yu, Tao1; Lin, Guo Zhong1; Zhang, Jia1; Zhang, Kuo2; Zhang, Hua3; Li, Yuan Chao4|
|WOS标题词||Science & Technology|
|研究领域[WOS]||Science & Technology - Other Topics|
|关键词[WOS]||OPEN-DOOR LAMINOPLASTY ; SPINAL-CORD TUMORS ; BILATERAL LAMINOTOMY ; LUMBAR SPINE ; IN-VITRO ; LAMINECTOMY ; MYELOPATHY ; DEFORMITY ; MODEL ; FLEXIBILITY|
Background: Recapping laminoplasty has become the frequently-used approach to the spinal canal when bone decompression of the vertebral canal is not the goal. However, what changes will occur after surgery, and whether recapping laminoplasty can actually reduce the risk of delayed deformities remains unknown.
Methodology: We designed an animal experiment using a caprine model, and partitioned the animals into in vitro and in vivo surgical groups. We performed recapping laminoplasty on one group and laminectomy on another group. These animals were sacrificed six months after operating, cervical spines removed, biomechanically tested, and these data were compared to determine whether the recapping laminoplasty technique leads to subsequent differences in range of motion. Image data were also obtained before the surgery and when the animals were killed. Besides, we investigated the initial differences in kinetics between recapping laminoplasty and laminectomy. We did this by comparing data obtained from biomechanical testing of in vitro-performed recapping laminoplasty and laminectomy. Finally, we investigated the effect that longitudinal distance has on cervical mechanics. This was determined by performing a two-level recapping laminoplasty, and then extending the laminoplasty to the next level and repeating the mechanical testing at each step.
Principal Findings: There were three mainly morphological changes at the six months after laminoplasty: volume reduction and bone nonunion of the recapping laminae, irregular fibrosis formation around the facet joints and re-implanted lamina-ligamentous complex. In the biomechanical test, comparing with laminectomy, recapping laminoplasty didn′t show significant differences in the immediate postoperative comparison, while recapping laminoplasty demonstrated significantly decreased motion in flexion/extension six months later. Inclusion of additional levels in the laminotomy procedure didn′t lead to changes in immediate biomechanics.
Conclusions: Recapping laminoplasty can′t fully restore the posterior structure, but still reduced the risk of delayed cervical instability in a caprine model.
|资助机构||National Natural Science Foundation of China|
|作者单位||1.Peking Univ, Hosp 3, Dept Neurosurg, Beijing 100871, Peoples R China|
2.Peking Univ, Hosp 3, Clin Epidemiol Res Ctr, Beijing 100871, Peoples R China
3.Shanghai Jiao Tong Univ, Sch Mech Engn, Shanghai 200030, Peoples R China
4.Dept Lab Anim Sci, Beijing, Peoples R China
|Si, Yu,Wang, Zhenyu,Yu, Tao,et al. Results of Cervical Recapping Laminoplasty: Gross Anatomical Changes, Biomechanical Evaluation at Different Time Points and Degrees of Level Involvement[J]. PLOS ONE,2014,9(6).|
|APA||Si, Yu.,Wang, Zhenyu.,Yu, Tao.,Lin, Guo Zhong.,Zhang, Jia.,...&Li, Yuan Chao.(2014).Results of Cervical Recapping Laminoplasty: Gross Anatomical Changes, Biomechanical Evaluation at Different Time Points and Degrees of Level Involvement.PLOS ONE,9(6).|
|MLA||Si, Yu,et al."Results of Cervical Recapping Laminoplasty: Gross Anatomical Changes, Biomechanical Evaluation at Different Time Points and Degrees of Level Involvement".PLOS ONE 9.6(2014).|