IR@PKUHSC  > 北京大学口腔医学院
学科主题口腔医学
Microstructure, mechanical properties, castability and in vitro biocompatibility of Ti-Bi alloys developed for dental applications
Qiu, K. J.1; Liu, Y.2; Zhou, F. Y.1; Wang, B. L.1; Li, L.1; Zheng, Y. F.1,2; Liu, Y. H.3
关键词Ti-Bi alloys Mechanical properties Castability Corrosion resistance Biocompatibility
刊名ACTA BIOMATERIALIA
2015-03-15
DOI10.1016/j.actbio.2015.01.009
15页:254-265
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Engineering, Biomedical ; Materials Science, Biomaterials
资助者National Basic Research Program of China (973 Program) ; National Science Fund for Distinguished Young Scholars ; National Natural Science Foundation of China ; NSFC/RGC Joint Research Scheme ; Beijing Municipal Science and Technology Project ; Project for Supervisor of Excellent Doctoral Dissertation of Beijing ; National Basic Research Program of China (973 Program) ; National Science Fund for Distinguished Young Scholars ; National Natural Science Foundation of China ; NSFC/RGC Joint Research Scheme ; Beijing Municipal Science and Technology Project ; Project for Supervisor of Excellent Doctoral Dissertation of Beijing
研究领域[WOS]Engineering ; Materials Science
关键词[WOS]COLLOIDAL BISMUTH SUBCITRATE ; TITANIUM-ALLOYS ; CORROSION BEHAVIOR ; BINARY-ALLOYS ; BIOMEDICAL APPLICATIONS ; ALZHEIMERS-DISEASE ; JOINT REPLACEMENT ; TI-6AL-4V ALLOYS ; MO ALLOYS ; NB ALLOYS
英文摘要

In this study, the microstructure, mechanical properties, castability, electrochemical behaviors, cytotoxicity and hemocompatibility of Ti-Bi alloys with pure Ti as control were systematically investigated to assess their potential applications in the dental field. The experimental results showed that, except for the Ti-20Bi alloy, the microstructure of all other Ti-Bi alloys exhibit single alpha-Ti phase, while Ti-20Bi alloy is consisted of mainly alpha-Ti phase and a small amount of BiTi2 and BiTi3 phases. The tensile strength, hardness and wear resistance of Ti-Bi alloys were demonstrated to be improved monotonically with the increase of Bi content. The castability test showed that Ti-2Bi alloy increased the castability of pure Ti by 11.7%. The studied Ti-Bi alloys showed better corrosion resistance than pure Ti in both AS (artificial saliva) and ASFL (AS containing 0.2% NaF and 0.3% lactic acid) solutions. The concentrations of both Ti ion and Bi ion released from Ti-Bi alloys are extremely low in AS, ASF (AS containing 0.2% NaF) and ASL (AS containing 0.3% lactic acid) solutions. However, in ASFL solution, a large number of Ti and Bi ions are released. In addition, Ti-Bi alloys produced no significant deleterious effect to L929 cells and MG63 cells, similar to pure Ti, indicating a good in vitro biocompatibility. Besides, both L929 and MG63 cells perform excellent cell adhesion ability on Ti-Bi alloys. The hemolysis test exhibited that Ti-Bi alloys have an ultra-low hemolysis percentage below 1% and are considered nonhemolytic. To sum up, the Ti-2Bi alloy exhibits the optimal comprehensive performance and has great potential for dental applications. (C) 2015 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

语种英语
所属项目编号2012CB619102 ; 2012CB619100 ; 51225101 ; 51431002 ; 31170909 ; 51361165101 ; Z131100005213002 ; 20121000101
资助者National Basic Research Program of China (973 Program) ; National Science Fund for Distinguished Young Scholars ; National Natural Science Foundation of China ; NSFC/RGC Joint Research Scheme ; Beijing Municipal Science and Technology Project ; Project for Supervisor of Excellent Doctoral Dissertation of Beijing ; National Basic Research Program of China (973 Program) ; National Science Fund for Distinguished Young Scholars ; National Natural Science Foundation of China ; NSFC/RGC Joint Research Scheme ; Beijing Municipal Science and Technology Project ; Project for Supervisor of Excellent Doctoral Dissertation of Beijing
WOS记录号WOS:000350520800025
Citation statistics
Cited Times:6[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65895
Collection北京大学口腔医学院
作者单位1.Harbin Engn Univ, Ctr Biomed Mat & Engn, Harbin 150001, Peoples R China
2.Peking Univ, Dept Mat Sci & Engn, Coll Engn, Beijing 100871, Peoples R China
3.Peking Univ, Gen Dent Dept, Sch Stomatol, Beijing 100081, Peoples R China
Recommended Citation
GB/T 7714
Qiu, K. J.,Liu, Y.,Zhou, F. Y.,et al. Microstructure, mechanical properties, castability and in vitro biocompatibility of Ti-Bi alloys developed for dental applications[J]. ACTA BIOMATERIALIA,2015,15:254-265.
APA Qiu, K. J..,Liu, Y..,Zhou, F. Y..,Wang, B. L..,Li, L..,...&Liu, Y. H..(2015).Microstructure, mechanical properties, castability and in vitro biocompatibility of Ti-Bi alloys developed for dental applications.ACTA BIOMATERIALIA,15,254-265.
MLA Qiu, K. J.,et al."Microstructure, mechanical properties, castability and in vitro biocompatibility of Ti-Bi alloys developed for dental applications".ACTA BIOMATERIALIA 15(2015):254-265.
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