|The incorporation of chlorhexidine in a two-step self-etching adhesive preserves dentin bond in vitro|
|Zhou, Jianfeng1; Tan, Jianguo1; Chen, Li1; Li, Deli2; Tan, Yao1|
|关键词||Chlorhexidine Bond degradation Matrix metalloproteinases Self-etching adhesives Microtensile bond test|
|刊名||JOURNAL OF DENTISTRY|
|WOS标题词||Science & Technology|
|类目[WOS]||Dentistry, Oral Surgery & Medicine|
|研究领域[WOS]||Dentistry, Oral Surgery & Medicine|
|关键词[WOS]||CARIES-AFFECTED DENTIN ; RESIN HYDROPHILICITY ; WATER SORPTION ; MATRIX METALLOPROTEINASES ; DEGRADATION ; ACTIVATION ; VIVO ; PERMEABILITY ; INHIBITION ; STRENGTH|
Objectives: To investigate whether the incorporation of chlorhexidine in a two-step self-etching adhesive can preserve dentin bond strengths.
Methods: Different amounts of 20% chlorhexidine digluconate were added directly to the primer of Clearfil SE Bond to prepare mixtures of four different concentrations of chlorhexidine: 0.05%, 0.1%, 0.5% and 1.0%. Sixteen extracted third molars were randomly divided into 4 groups. Each group corresponded to one of the four chlorhexidine concentrations. Each of the 16 teeth was sectioned into two halves. One half was bonded with Clearfil SE Bond without chlorhexidine, and the other half was bonded with Clearfil SE Bond containing different concentrations of chlorhexidine. Specimens were stored in 0.9% NaCl containing 0.02% sodium azide at 37 degrees C. Microtensile bond strengths were tested 24 h after specimen preparation or 12 months later. The modes of fractures were examined under a stereomicroscope.
Results: Twelve-month storage resulted in significant bond strength reduction of all control groups (p < 0.05). When incorporated in SE Bond primer, chlorhexidine preserved dentin bond in the 0.1%, 0.5% and 1.0% chlorhexidine group (p < 0.05); in the 0.05% group, there is no statistical difference of bond strength between control group and experimental group tested at the 12-month period (p > 0.05).
Conclusions: When incorporated in the primer of Clearfil SE Bond, chlorhexidine can preserve dentin bond as long as the concentration of chlorhexidine in the primer is higher than or equal to 0.1%. (C) 2009 Elsevier Ltd. All rights reserved.
|作者单位||1.Peking Univ, Sch & Hosp Stomatol, Dept Prosthodont, Beijing 100081, Peoples R China|
2.Peking Univ, Sch & Hosp Stomatol, Dept Gen Dent, Beijing 100101, Peoples R China
|Zhou, Jianfeng,Tan, Jianguo,Chen, Li,et al. The incorporation of chlorhexidine in a two-step self-etching adhesive preserves dentin bond in vitro[J]. JOURNAL OF DENTISTRY,2009,37(10):807-812.|
|APA||Zhou, Jianfeng,Tan, Jianguo,Chen, Li,Li, Deli,&Tan, Yao.(2009).The incorporation of chlorhexidine in a two-step self-etching adhesive preserves dentin bond in vitro.JOURNAL OF DENTISTRY,37(10),807-812.|
|MLA||Zhou, Jianfeng,et al."The incorporation of chlorhexidine in a two-step self-etching adhesive preserves dentin bond in vitro".JOURNAL OF DENTISTRY 37.10(2009):807-812.|