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IR@PKUHSC  > 北京大学临床肿瘤学院  > 流行病学研究室  > 期刊论文
学科主题: 临床医学
题名:
Implementation of gastric cancer screening - The global experience
作者: Leja, Marcis1; You, Weicheng2; Camargo, M. Constanza3; Saito, Hiroshi4
关键词: Biomarkers ; Gastric cancer ; Helicobacter pylori ; Precancerous lesions ; Screening
刊名: BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
发表日期: 2014-12-01
DOI: 10.1016/j.bpg.2014.09.005
卷: 28, 期:6, 页:1093-1106
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology
研究领域[WOS]: Gastroenterology & Hepatology
关键词[WOS]: HELICOBACTER-PYLORI ERADICATION ; SERUM PEPSINOGEN ; STOMACH-CANCER ; HIGH-RISK ; COST-EFFECTIVENESS ; FOLLOW-UP ; PRECANCEROUS LESIONS ; MULTIPLEX SEROLOGY ; GENE POLYMORPHISMS ; CHINESE POPULATION
英文摘要:

Gastric cancer (GC) is still an important global healthcare problem, and in absolute figures it is going to remain at the present level in foreseeable future. In general, survival′ of patients with GC is poor mainly due to advanced-stage diagnosis. Early-stage GC can be cured by endoscopic resection or less invasive surgical treatment. Unfortunately, there is no appropriate screening strategy available for global application. This article provides a description of established national and regional GC screening programs and the screening modalities used. This review also summarizes current approaches to develop cancer-screening biomarkers. Although candidates with initial promising results have been suggested, moving discovery into clinical practice is still a major challenge. Well-designed biomarker studies, with systematic validation steps, are needed to decrease the burden of this fatal disease. (C) 2014 Elsevier Ltd. All rights reserved.

语种: 英语
所属项目编号: 4
项目资助者: National Research Program in Public Health priority
WOS记录号: WOS:000347364500013
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65957
Appears in Collections:北京大学临床肿瘤学院_流行病学研究室_期刊论文

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作者单位: 1.Univ Latvia, Fac Med, LV-1006 Riga, Latvia
2.Peking Univ Canc Hosp & Inst, Dept Canc Epidemiol, Key Lab Carcinogenesis & Translat Res, Minist Educ, Beijing 100142, Peoples R China
3.NCI, Div Canc Epidemiol & Genet, Rockville, MD USA
4.Natl Canc Ctr, Res Ctr Canc Prevent & Detect, Canc Screening Assessment & Management Div, Tokyo 1040045, Japan

Recommended Citation:
Leja, Marcis,You, Weicheng,Camargo, M. Constanza,et al. Implementation of gastric cancer screening - The global experience[J]. BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY,2014,28(6):1093-1106.
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