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学科主题临床医学
Implementation of gastric cancer screening - The global experience
Leja, Marcis1; You, Weicheng2; Camargo, M. Constanza3; Saito, Hiroshi4
关键词Biomarkers Gastric cancer Helicobacter pylori Precancerous lesions Screening
刊名BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
2014-12-01
DOI10.1016/j.bpg.2014.09.005
28期:6页:1093-1106
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Gastroenterology & Hepatology
研究领域[WOS]Gastroenterology & Hepatology
关键词[WOS]HELICOBACTER-PYLORI ERADICATION ; SERUM PEPSINOGEN ; STOMACH-CANCER ; HIGH-RISK ; COST-EFFECTIVENESS ; FOLLOW-UP ; PRECANCEROUS LESIONS ; MULTIPLEX SEROLOGY ; GENE POLYMORPHISMS ; CHINESE POPULATION
英文摘要

Gastric cancer (GC) is still an important global healthcare problem, and in absolute figures it is going to remain at the present level in foreseeable future. In general, survival′ of patients with GC is poor mainly due to advanced-stage diagnosis. Early-stage GC can be cured by endoscopic resection or less invasive surgical treatment. Unfortunately, there is no appropriate screening strategy available for global application. This article provides a description of established national and regional GC screening programs and the screening modalities used. This review also summarizes current approaches to develop cancer-screening biomarkers. Although candidates with initial promising results have been suggested, moving discovery into clinical practice is still a major challenge. Well-designed biomarker studies, with systematic validation steps, are needed to decrease the burden of this fatal disease. (C) 2014 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000347364500013
项目编号4
资助机构National Research Program in Public Health priority
引用统计
被引频次:21[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65957
专题北京大学临床肿瘤学院_流行病学研究室
北京大学临床肿瘤学院_党院办公室
作者单位1.Univ Latvia, Fac Med, LV-1006 Riga, Latvia
2.Peking Univ Canc Hosp & Inst, Dept Canc Epidemiol, Key Lab Carcinogenesis & Translat Res, Minist Educ, Beijing 100142, Peoples R China
3.NCI, Div Canc Epidemiol & Genet, Rockville, MD USA
4.Natl Canc Ctr, Res Ctr Canc Prevent & Detect, Canc Screening Assessment & Management Div, Tokyo 1040045, Japan
推荐引用方式
GB/T 7714
Leja, Marcis,You, Weicheng,Camargo, M. Constanza,et al. Implementation of gastric cancer screening - The global experience[J]. BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY,2014,28(6):1093-1106.
APA Leja, Marcis,You, Weicheng,Camargo, M. Constanza,&Saito, Hiroshi.(2014).Implementation of gastric cancer screening - The global experience.BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY,28(6),1093-1106.
MLA Leja, Marcis,et al."Implementation of gastric cancer screening - The global experience".BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY 28.6(2014):1093-1106.
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