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Microbial transformation of curdione by Mucor spinosus
Ma, XC; Ye, M; Wu, LJ; Guo, DA
关键词curdione biotransformation selective hydrogenation Mucor spinosus
刊名ENZYME AND MICROBIAL TECHNOLOGY
2006-02-01
38期:3-4页:367-371
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biotechnology & Applied Microbiology
研究领域[WOS]Biotechnology & Applied Microbiology
关键词[WOS]ZEDOARIAE RHIZOMA ; SESQUITERPENES ; METABOLISM
英文摘要

Twenty strains of filamentous fungi (from nine genera) and four species of bacteria were screened for their capabilities to transform curdione (1). Site-specific hydroxylation and epoxidation of the substrate by Mucor spinosus AS 3.3450 were reported. Five compounds were obtained, and their structures were identified as 1 beta,10 alpha-epoxycurdione (2), 1 alpha,10 beta-epoxycurdione (3), 2 beta-hydroxycurdione (4), 11-hydroxycurdione (5) and 2 beta, 11-dihydroxycurdione (6), respectively, on the basis of their spectral data. Among them, products 5 and 6 are new compounds. The biotransformation kinetics was also investigated. (c) 2005 Elsevier Inc. All rights reserved.

语种英语
WOS记录号WOS:000234535100008
引用统计
被引频次:28[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65970
专题北京大学药学院
作者单位1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
2.Shenyang Pharmaceut Univ, Sch Tradit Chinese Med, Shenyang 110016, Peoples R China
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GB/T 7714
Ma, XC,Ye, M,Wu, LJ,et al. Microbial transformation of curdione by Mucor spinosus[J]. ENZYME AND MICROBIAL TECHNOLOGY,2006,38(3-4):367-371.
APA Ma, XC,Ye, M,Wu, LJ,&Guo, DA.(2006).Microbial transformation of curdione by Mucor spinosus.ENZYME AND MICROBIAL TECHNOLOGY,38(3-4),367-371.
MLA Ma, XC,et al."Microbial transformation of curdione by Mucor spinosus".ENZYME AND MICROBIAL TECHNOLOGY 38.3-4(2006):367-371.
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