北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 基础医学院  > 期刊论文
学科主题: 基础医学
题名:
Changing trends and serotype distribution of Shigella species in Beijing from 1994 to 2010
作者: Mao, Yuanli1; Cui, Enbo1; Bao, Chunmei1; Liu, Zhenhong1; Chen, Suming1; Zhang, Juling1; Wang, Huan1; Zhang, Chenglong1; Zou, Jing2; Klena, John D.3; Zhu, Baoli2; Qu, Fen1; Wang, Zhiyun2
关键词: Shigellosis ; Shigella ; Serotype ; Beijing hospital
刊名: GUT PATHOGENS
发表日期: 2013-08-07
DOI: 10.1186/1757-4749-5-21
卷: 5
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology ; Microbiology
研究领域[WOS]: Gastroenterology & Hepatology ; Microbiology
关键词[WOS]: POPULATION-BASED SURVEILLANCE ; BACILLARY DYSENTERY ; VACCINE DEVELOPMENT ; DISEASE BURDEN ; FLEXNERI 4C ; DIARRHEA ; STRAIN ; INFECTIONS ; PATTERNS ; CHINA
英文摘要:

Shigella species are a common cause of acute diarrheal disease in China. In this study, we characterized the changing trends and serotype distribution of Shigella species in Beijing from 1994 to 2010. A total of 5999 Shigella strains were isolated and serotyped from the 302nd Hospital in Beijing. The annual number of Shigella isolates reached a peak (n = 1192; 19.84%) in 1996 and then decreased annually, reaching the lowest point (n = 24; 0.41%) in 2010. S. flexneri 2a and S. sonnei were the most frequently isolated Shigella, with their respective isolates making up 53.3% and 27.6% of the total. Isolates of S. flexneri 4c, 4a, and x made up 3% respectively of the total isolates. Significant decreases in percentage of S. flexneri over time were observed. S. sonnei surpassed S. flexneri 2a as the predominant serotype in 2000. Most isolates were recovered from July to September; 13.6% of the isolates were recovered from children aged 0 to 5 years, and 16% were recovered from those aged 21 to 25 years. S. flexneri 2a and 5 were recovered mostly from males (33.41%, p < 0.001; and 0.46%, p < 0.001%; respectively), whereas S. flexneri 2b and 6, and S. sonnei were most often isolated from females. Continuous monitoring of Shigella showed that all 4 species and 27 serotypes were present in Beijing, China, during the study period. The emergence of S. sonnei and the overall decreasing isolation rate of Shigella in Beijing can potentially aid in the development of vaccine and control strategies for shigellosis in the city.

语种: 英语
所属项目编号: BWS11C073
项目资助者: Chinese Military Medical and Technology Twelfth Five-Year Science and Research Key Program Fund
WOS记录号: WOS:000323005100001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/66065
Appears in Collections:基础医学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.302nd Hosp Peoples Liberat Army, Clin Diagnost Ctr, Beijing 100039, Peoples R China
2.Chinese Acad Sci, Inst Microbiol, Beijing 100101, Peoples R China
3.Peking Univ, Sch Basic Med Sci, Beijing 100083, Peoples R China

Recommended Citation:
Mao, Yuanli,Cui, Enbo,Bao, Chunmei,et al. Changing trends and serotype distribution of Shigella species in Beijing from 1994 to 2010[J]. GUT PATHOGENS,2013,5.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Mao, Yuanli]'s Articles
[Cui, Enbo]'s Articles
[Bao, Chunmei]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Mao, Yuanli]‘s Articles
[Cui, Enbo]‘s Articles
[Bao, Chunmei]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace