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Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues
Chen, Bifeng1; Li, Wei2; Lv, Cong1; Zhao, Manman2; Jin, Hongwei1; Jin, Hongfang2; Du, Junbao2; Zhang, Liangren1; Tang, Xinjing1
刊名ANALYST
2013
DOI10.1039/c2an36113b
138期:3页:946-951
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Analytical
资助者National Basic Research Program of China (&prime ; 973&prime ; Program) ; National Natural Science Foundation of China ; Program for New Century Excellent Talents in University ; National Basic Research Program of China (&prime ; 973&prime ; Program) ; National Natural Science Foundation of China ; Program for New Century Excellent Talents in University
研究领域[WOS]Chemistry
关键词[WOS]H2S ; RAT ; ANGIOGENESIS ; PERFUSION ; BLOOD ; MICE
英文摘要

A coumarin-based fluorescence chemoprobe was developed and evaluated for the selective and sensitive detection of hydrogen sulfide in degassed PBS buffers and fetal bovine serum. Fluorescence detection of hydrogen sulfide in living cells was also successfully achieved using two-photon confocal fluorescence imaging. Further in situ visualization of endogenous H2S was realized in cardiac tissues of normal rats and atherosclerosis (AS) rats.

语种英语
所属项目编号2013CB933800 ; 21072015 ; NCET10-0203
资助者National Basic Research Program of China (&prime ; 973&prime ; Program) ; National Natural Science Foundation of China ; Program for New Century Excellent Talents in University ; National Basic Research Program of China (&prime ; 973&prime ; Program) ; National Natural Science Foundation of China ; Program for New Century Excellent Talents in University
WOS记录号WOS:000312944400032
Citation statistics
Cited Times:82[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66104
Collection北京大学药学院
作者单位1.Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
2.Peking Univ, Dept Pediat, Hosp 1, Beijing 100034, Peoples R China
Recommended Citation
GB/T 7714
Chen, Bifeng,Li, Wei,Lv, Cong,et al. Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues[J]. ANALYST,2013,138(3):946-951.
APA Chen, Bifeng.,Li, Wei.,Lv, Cong.,Zhao, Manman.,Jin, Hongwei.,...&Tang, Xinjing.(2013).Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues.ANALYST,138(3),946-951.
MLA Chen, Bifeng,et al."Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues".ANALYST 138.3(2013):946-951.
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