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Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues
Chen, Bifeng1; Li, Wei2; Lv, Cong1; Zhao, Manman2; Jin, Hongwei1; Jin, Hongfang2; Du, Junbao2; Zhang, Liangren1; Tang, Xinjing1
刊名ANALYST
2013
DOI10.1039/c2an36113b
138期:3页:946-951
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Analytical
研究领域[WOS]Chemistry
关键词[WOS]H2S ; RAT ; ANGIOGENESIS ; PERFUSION ; BLOOD ; MICE
英文摘要

A coumarin-based fluorescence chemoprobe was developed and evaluated for the selective and sensitive detection of hydrogen sulfide in degassed PBS buffers and fetal bovine serum. Fluorescence detection of hydrogen sulfide in living cells was also successfully achieved using two-photon confocal fluorescence imaging. Further in situ visualization of endogenous H2S was realized in cardiac tissues of normal rats and atherosclerosis (AS) rats.

语种英语
WOS记录号WOS:000312944400032
项目编号2013CB933800 ; 21072015 ; NCET10-0203
资助机构National Basic Research Program of China (&prime ; 973&prime ; Program) ; National Natural Science Foundation of China ; Program for New Century Excellent Talents in University
引用统计
被引频次:88[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66104
专题北京大学药学院
北京大学医学部管理机构_医学部
北京大学药学院_天然药物与仿生药物国家重点实验室
北京大学药学院_药物化学系
北京大学第一临床医学院_儿科
作者单位1.Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
2.Peking Univ, Dept Pediat, Hosp 1, Beijing 100034, Peoples R China
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GB/T 7714
Chen, Bifeng,Li, Wei,Lv, Cong,et al. Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues[J]. ANALYST,2013,138(3):946-951.
APA Chen, Bifeng.,Li, Wei.,Lv, Cong.,Zhao, Manman.,Jin, Hongwei.,...&Tang, Xinjing.(2013).Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues.ANALYST,138(3),946-951.
MLA Chen, Bifeng,et al."Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues".ANALYST 138.3(2013):946-951.
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