IR@PKUHSC  > 北京大学第三临床医学院  > 心血管内科
学科主题临床医学
Mode of myosin transportation in living cells studied by single particle tracking
Liang, Zhang-Yi; Xu, Ning; Guan, Ying-Hua; Zhang, You-Yi; Zhao, Xin-Sheng
关键词single particle tracking live cell alpha(1A)-adrenergic receptor myosin assay
刊名CHINESE JOURNAL OF CHEMICAL PHYSICS
2007-08-27
DOI10.1088/1.674-0068/20/04/445-448
20期:4页:445-448
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Physics, Atomic, Molecular & Chemical
研究领域[WOS]Physics
关键词[WOS]HAND-OVER-HAND ; ALPHA(1)-ADRENOCEPTOR SUBTYPES ; KINETIC MECHANISM ; STEP-SIZE ; MOTOR ; ALPHA(1B)-ADRENOCEPTOR ; INTERNALIZATION ; LOCALIZATION ; KINESIN ; ACTIN
英文摘要

The transport of internalized alpha(1A)-adrenergic receptor (alpha(1A)-AR) by myosin protein in live cells was studied. The technique of single particle tracking by fluorescence imaging with high temporal and spatial resolution was used. The endosomes of alpha(1A)-AR were transported along actin filaments in a step-by-step mode. The average step-size in different time resolutions is consistent with the step-size of myosin assay in vitro. With the simulation of the stepwise traces in different time resolutions, we found that the kinetic process of each step is in coherence with the single myosin assay in vitro.

语种英语
WOS记录号WOS:000249465100019
Citation statistics
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66108
Collection北京大学第三临床医学院_心血管内科
作者单位1.Minist Educ, Key Lab Mol Cardiovasc Sci, Beijing 100083, Peoples R China
2.Peking Univ Third Hosp, Inst Vasc Med, Beijing 100083, Peoples R China
3.Peking Univ, Coll Chem & Mol Engn, Beijing Natl Lab Mol Sci, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100871, Peoples R China
4.Peking Univ, Coll Chem & Mol Engn, Dept Biol Chem, Beijing 100871, Peoples R China
Recommended Citation
GB/T 7714
Liang, Zhang-Yi,Xu, Ning,Guan, Ying-Hua,et al. Mode of myosin transportation in living cells studied by single particle tracking[J]. CHINESE JOURNAL OF CHEMICAL PHYSICS,2007,20(4):445-448.
APA Liang, Zhang-Yi,Xu, Ning,Guan, Ying-Hua,Zhang, You-Yi,&Zhao, Xin-Sheng.(2007).Mode of myosin transportation in living cells studied by single particle tracking.CHINESE JOURNAL OF CHEMICAL PHYSICS,20(4),445-448.
MLA Liang, Zhang-Yi,et al."Mode of myosin transportation in living cells studied by single particle tracking".CHINESE JOURNAL OF CHEMICAL PHYSICS 20.4(2007):445-448.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
谷歌学术
谷歌学术Similar articles in
[Liang, Zhang-Yi]'s Articles
[Xu, Ning]'s Articles
[Guan, Ying-Hua]'s Articles
百度学术
百度学术Similar articles in
[Liang, Zhang-Yi]'s Articles
[Xu, Ning]'s Articles
[Guan, Ying-Hua]'s Articles
必应学术
必应学术Similar articles in
[Liang, Zhang-Yi]'s Articles
[Xu, Ning]'s Articles
[Guan, Ying-Hua]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.