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Diagnostic value of different patient positions during expiratory low-dose thin-layer MDCT for evaluating air trapping after allogeneic hematopoietic stem cell transplantation
Zhang, X. -J.1; Gao, F.1; Zhao, J.2; He, J-X.3; Chen, J.1; Wei, H. -J.1; Chen, B.4
关键词Thin-layer MDCT Air trapping Supine position Prone position Expiratory phase
刊名EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
2014-12-01
18期:24页:3779-3787
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]BRONCHIOLITIS OBLITERANS SYNDROME ; HIGH-RESOLUTION CT ; SECTION CT ; LUNG TRANSPLANTATION
英文摘要

OBJECTIVE: To investigate the diagnostic value of different patient positions during expiratory low-dose thin-layer multidetector computed tomography (MDCT) for detect ing air trapping after allogeneic hematopoietic stem cell transplantation (allo-HSCT).

PATIENTS AND METHODS: Expiratory lung MDCT scanning was done for 51 post-allo-HSCT patients in both the supine and prone positions to determine if they had air trapping lesions. We assessed the volume fraction of an air trapping region (CT value of <= 700HU at expiratory phase) against the whole lung area with a GE workstation and graded these results.

RESULTS: In the supine position, multiple air trapping lesions were found in 16 of 51 patients, which were scattered and mainly distributed in the dorsal sides of both lower lobes. In the prone position, in addition to these 15 patients, air trapping lesions were also found in 11 other patients, which were mainly distributed in the anterior load-bearing area of the lung lower lobes and lobe-connected areas. Compared with that in the supine position, the graded score of air trapping in the prone position was significantly different (p = 0.006).

CONCLUSIONS: When performing expiratory thin-layer MDCT for patients with chronic rejection reactions after allo-HSCT, scanning in the prone position should also be performed, not only to more accurately observe lesions, but also for a preliminary evaluation of air trapping severity. This provides a basis for an early clinical diagnosis and treatment.

语种英语
WOS记录号WOS:000352210900011
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66140
专题北京大学公共卫生学院
作者单位1.China Aerosp Corp, Cent Hosp, Dept Neurol, Beijing, Peoples R China
2.China Aerosp Corp, Cent Hosp, Dept Radiol, Beijing, Peoples R China
3.Nanchang Univ, Dept Ultrasonog, Affiliated Hosp 1, Nanchang, Peoples R China
4.Beijing Univ, Dept Med, Sch Publ Hlth, Beijing 100871, Peoples R China
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Zhang, X. -J.,Gao, F.,Zhao, J.,et al. Diagnostic value of different patient positions during expiratory low-dose thin-layer MDCT for evaluating air trapping after allogeneic hematopoietic stem cell transplantation[J]. EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES,2014,18(24):3779-3787.
APA Zhang, X. -J..,Gao, F..,Zhao, J..,He, J-X..,Chen, J..,...&Chen, B..(2014).Diagnostic value of different patient positions during expiratory low-dose thin-layer MDCT for evaluating air trapping after allogeneic hematopoietic stem cell transplantation.EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES,18(24),3779-3787.
MLA Zhang, X. -J.,et al."Diagnostic value of different patient positions during expiratory low-dose thin-layer MDCT for evaluating air trapping after allogeneic hematopoietic stem cell transplantation".EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES 18.24(2014):3779-3787.
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