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学科主题: 口腔医学
题名:
Odontogenic myxoma - A clinicopathologic study of 25 cases
作者: Li, Tie-Jun; Sun, Li-Sha; Luo, Hai-Yan
刊名: ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
发表日期: 2006-12-01
卷: 130, 期:12, 页:1799-1806
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medical Laboratory Technology ; Medicine, Research & Experimental ; Pathology
研究领域[WOS]: Medical Laboratory Technology ; Research & Experimental Medicine ; Pathology
关键词[WOS]: JAWS ; TUMORS ; FEATURES ; NIGERIA ; TISSUE
英文摘要:

Context.-Odontogenic myxoma is an uncommon tumor that has the potential for extensive destruction of the jaws.

Objective.-To document the clinical, pathologic, and behavioral features of odontogenic myxomas.

Design.-Histologic and immunocytochemical examinations were performed on odontogenic myxomas from 25 Chinese patients. Clinical and available follow-up data were analyzed.

Results.-In the present series, 13 were male and 12 female. The age at diagnosis ranged from 6 to 66 years, with a mean age of 28.8 years. Twelve tumors involved the mandible and 13 occurred in the maxilla, with a predilection for posterior areas. The posterior maxillary tumors frequently (9/10) involved the maxillary sinus. Of the 23 cases with radiographic records, 22 lesions presented with a multilocular appearance. Although 80% of the mandibular lesions showed a well-defined border, only 33.3% of the maxillary tumors were well-defined. Histologically, odontogenic myxomas were mainly composed of spindled or stellate-shaped cells in a mucoid-rich intercellular matrix. Tumors containing noticeable fibrous components were evident in 13 cases. Apart from 5 cases treated conservatively by enucleation, the remaining 20 cases were treated by relatively radical procedures, including block/segmental resection and partial or total maxillectomy or mandibulectomy. Follow-up data were available on 22 patients and only 1 patient initially treated by enucleation had a recurrence.

Conclusions.-Odontogenic myxomas have a very bland histologic appearance that lacks atypia and may easily lead to misdiagnosis. The tumors are infiltrative with no capsulation and may recur after inadequate surgery.

语种: 英语
WOS记录号: WOS:000242645000016
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/66159
Appears in Collections:北京大学口腔医学院_口腔病理科_期刊论文

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作者单位: Peking Univ, Sch & Hosp Stomatol, Dept Oral Pathol, Beijing 100081, Peoples R China

Recommended Citation:
Li, Tie-Jun,Sun, Li-Sha,Luo, Hai-Yan. Odontogenic myxoma - A clinicopathologic study of 25 cases[J]. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE,2006,130(12):1799-1806.
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