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学科主题: 临床医学
题名:
Histopathological Implications of Aspergillus Infection in Lung
作者: Tochigi, Naobumi1; Okubo, Yoichiro1; Ando, Tsunehiro1; Wakayama, Megumi1; Shinozaki, Minoru1; Gocho, Kyoko2; Hata, Yoshinobu3; Ishiwatari, Takao1; Nemoto, Tetsuo1; Shibuya, Kazutoshi1,4
刊名: MEDIATORS OF INFLAMMATION
发表日期: 2013
DOI: 10.1155/2013/809798
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Cell Biology ; Immunology
研究领域[WOS]: Cell Biology ; Immunology
关键词[WOS]: INVASIVE PULMONARY ASPERGILLOSIS ; HALO SIGN ; COMPUTED-TOMOGRAPHY ; DIAGNOSIS ; EPIDEMIOLOGY ; FEATURES ; DISEASE
英文摘要:

This paper opens with a discussion on the significance of invasive fungal infections in advanced contemporary medicine, with an emphasis on the intractability of disease management and the difficulties of diagnosis. This is followed by a discussion concerning classification, histopathological features, and pathophysiology. While it has been largely accepted that Aspergillus species is recognized by cellular receptors and attacked by neutrophils, the radiological and macroscopic findings linking infection with neutropenia remain unconfirmed. In an effort to gain a better understanding of the pathophysiology and pathogenesis of invasive aspergillosis, we wish to emphasize the utility of radiological and histopathological examinations since these can provide detailed information on the extremely complex interaction between the causative microbes and tissue responses. A review of noninvasive or semi- invasive aspergillosis is also provided, with particular emphasis on chronic necrotizing pulmonary aspergillosis, which is recognized as a transition form of simple pulmonary aspergilloma and invasive pulmonary aspergillosis, although few findings have been reported in this area.

语种: 英语
所属项目编号: 24790364 ; 23-19 ; 21 ; 28 ; 24-11 ; 16 ; 27
项目资助者: KAKENHI ; Ministry of Education, Culture, Sports, Science, and Technology of Japan ; Foundation for the Advancement of Medical Science ; Yokohama Foundation for the Advancement of Medical Science ; KurozumiMedical Foundation
WOS记录号: WOS:000327656500001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/66189
Appears in Collections:北京大学第一临床医学院_皮肤性病科_期刊论文

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作者单位: 1.Toho Univ, Sch Med, Dept Surg Pathol, Ota Ku, Tokyo 1438541, Japan
2.Toho Univ, Sch Med, Div Pulm Med, Ota Ku, Tokyo 1438541, Japan
3.Toho Univ, Sch Med, Div Chest Surg, Ota Ku, Tokyo 1438541, Japan
4.Peking Univ, Dept Dermatol, Hosp 1, Beijing 100034, Peoples R China

Recommended Citation:
Tochigi, Naobumi,Okubo, Yoichiro,Ando, Tsunehiro,et al. Histopathological Implications of Aspergillus Infection in Lung[J]. MEDIATORS OF INFLAMMATION,2013.
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