|Impact of diabetes on diagnostic delay for pulmonary tuberculosis in Beijing|
|Chen, H-G.1; Liu, M.1; Jiang, S-W.2; Gu, F-H.1; Huang, S-P.3; Gao, T-J.4; Zhang, Z-G.4|
|关键词||diabetes mellitus tuberculosis diagnostic delay impact factor|
|刊名||INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE|
|WOS标题词||Science & Technology|
|类目[WOS]||Infectious Diseases ; Respiratory System|
|研究领域[WOS]||Infectious Diseases ; Respiratory System|
|关键词[WOS]||CHINA ; MELLITUS ; TIME ; TB|
SETTING: Delays in the diagnosis of pulmonary tuberculosis (PTB) increase the risk of transmission and severity of the disease. Little information is available on PTB pdatients with diabetes mellitus (DM).
OBJECTIVES: To examine the impact of DM on delays in diagnosing PTB and the effect of diagnostic delay on the clinical presentation of PTB among patients in Beijing, China.
DESIGN: In a cross-sectional study conducted in two PTB dispensaries of Beijing, all confirmed PTB patients were screened for DM. Data relating to diagnostic delay and clinical presentation of PTB were collected and analysed.
RESULTS: Of 1126 PTB patients selected, 182 (16.2%) were identified as having DM. The median delay for PTB patients with DM (25 days) was significantly higher than that of PTB patients without DM (6 days). In a subgroup analysis, diagnostic delay was associated with smear positivity among PTB patients with DM (OR 3.10, 95%CI 1.66-5.76) and associated with smear positivity (OR 4.38, 95%CI 3.19-6.04), pulmonary cavities (OR 2.62, 95%CI 1.85-3.71) and more symptoms (OR 1.81, 95%CI 1.20-2.73) among PTB patients without DM.
CONCLUSIONS: DM was associated with longer diagnostic delays, which in turn was associated with more serious clinical presentations of PTB. It is thus necessary to examine risk factors associated with diagnostic delay among PTB patients with and without DM.
|资助机构||Chinese National Programs for High Technology Research and Development (863 program)|
|作者单位||1.Peking Univ, Dept Epidemiol & Biostat, Sch Publ Hlth, Beijing 100191, Peoples R China|
2.China Ctr Dis Control & Prevent, Natl Ctr TB Control & Prevent, Beijing, Peoples R China
3.Fangshan Dispensary, Beijing, Fangshan Distri, Peoples R China
4.Changping Dispensary, Beijing, Changping Distr, Peoples R China
|Chen, H-G.,Liu, M.,Jiang, S-W.,et al. Impact of diabetes on diagnostic delay for pulmonary tuberculosis in Beijing[J]. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE,2014,18(3):267-271.|
|APA||Chen, H-G..,Liu, M..,Jiang, S-W..,Gu, F-H..,Huang, S-P..,...&Zhang, Z-G..(2014).Impact of diabetes on diagnostic delay for pulmonary tuberculosis in Beijing.INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE,18(3),267-271.|
|MLA||Chen, H-G.,et al."Impact of diabetes on diagnostic delay for pulmonary tuberculosis in Beijing".INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE 18.3(2014):267-271.|