北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学药学院  > 化学生物学系  > 期刊论文
学科主题: 药学
题名:
BF3 center dot OEt2-Promoted Diastereoselective Diacetoxylation of Alkenes by PhI(OAc)(2)
作者: Zhong, Wenhe; Yang, Jun; Meng, Xiangbao; Li, Zhongjun
刊名: JOURNAL OF ORGANIC CHEMISTRY
发表日期: 2011-12-16
DOI: 10.1021/jo201752y
卷: 76, 期:24, 页:9997-10004
收录类别: SCI ; IC ; CCR
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Organic
研究领域[WOS]: Chemistry
关键词[WOS]: HYPERVALENT IODINE(III) REAGENTS ; ACTIVATED IODOSYLBENZENE MONOMER ; CIS-DIHYDROXYLATION ; OXIDATIVE CLEAVAGE ; ASYMMETRIC DIHYDROXYLATION ; SYN-DIHYDROXYLATION ; MOLECULAR-OXYGEN ; EPOXIDATION ; ACID ; EFFICIENT
英文摘要:

Selective syn and anti diacetoxylations of alkenes have been achieved using a PhI(OAc)(2)/BF3 center dot OEt2 system in the presence and absence of water, respectively. A broad range of substrates including electron-deficient alkenes (such as alpha,beta-unsaturated esters) could be elaborated efficiently at room temperature with this methodology, furnishing the desired products in good to excellent yields and diastereoselectivity. In particular, a multigram-scale diastereoselective diacetoxylation of methyl cinnamate (5.00 g) was also accomplished in a few hours, maintaining the same efficiency as small-scale reaction. This novel methodology provides an alternative approach for the preparation of various 1,2-diols.

语种: 英语
所属项目编号: 21072017 ; 20732001 ; 2012CB822100
项目资助者: National Natural Science Foundation of China (NSFC) ; National Basic Research Program of China
WOS记录号: WOS:000297715900012
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/66234
Appears in Collections:北京大学药学院_化学生物学系_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, State Key Lab Nat & Biomimet Drugs, Dept Biol Chem, Sch Pharmaceut Sci, Beijing 100191, Peoples R China

Recommended Citation:
Zhong, Wenhe,Yang, Jun,Meng, Xiangbao,et al. BF3 center dot OEt2-Promoted Diastereoselective Diacetoxylation of Alkenes by PhI(OAc)(2)[J]. JOURNAL OF ORGANIC CHEMISTRY,2011,76(24):9997-10004.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhong, Wenhe]'s Articles
[Yang, Jun]'s Articles
[Meng, Xiangbao]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhong, Wenhe]‘s Articles
[Yang, Jun]‘s Articles
[Meng, Xiangbao]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace