IR@PKUHSC  > 北京大学第一临床医学院  > 内分泌内科
学科主题临床医学
The prevalence of hyperuricemia in a population of the coastal city of Qingdao, China
Nan, Hairong; Qiao, Qing; Dong, Yanhu; Gao, Weiguo; Tang, Bin; Qian, Rongli; Tuomilehto, Jaakko
关键词serum uric acid hyperuricemia gout prevalence Chinese
刊名JOURNAL OF RHEUMATOLOGY
2006-07-01
33期:7页:1346-1350
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Rheumatology
研究领域[WOS]Rheumatology
关键词[WOS]SERUM URIC-ACID ; TAIWAN ABORIGINES ; RISK-FACTORS ; GOUT ; EPIDEMIOLOGY ; PLASMA ; URATE
英文摘要

Objective. Hyperuricemia and gout have shown an increase worldwide. Data are lacking for the prevalence of hyperuricemia and gout and their correlates in China. We studied the occurrence of these conditions in Chinese adults in the city of Qingdao.

Methods. A population-based cross-sectional survey for hyperuricemia and gout was performed among 2438 adults (1535 women, 903 men; aged 20-74 yrs) in 2002. Fasting serum uric acid (UA) and lipid profiles were determined, as well as height, weight, and blood pressure. Hyperuricemia was defined as serum UA levels > 420 mu mol/l in men and > 360 mu mol/l in women. Diagnosis of gout was self-reported. Complete biochemical and questionnaire data were available for analysis from 1303 women and 720 men.

Results. The age-standardized prevalence was 25.3% for hyperuricemia and 0.36% for gout in adults aged 20 to 74 years. Hyperuricemia was more prevalent in men than in women (32.1% vs 21.8%; p < 0.001). Age-adjusted mean serum UA level was 389.3 mu mol/l in men and 315.7 mu mol/l in women. Serum UA increased with age in women only (p for trend < 0.001). Body mass index and serum triglycerides had the strongest associations with serum UA in both genders, followed by alcohol drinking and diastolic blood pressure in men, and systolic blood pressure and total cholesterol in women.

Conclusion. The prevalence of hyperuricemia in the urban adult population in Qingdao city is high, while the frequency of gout is lower. Obesity, hypertension, and dyslipidemia are the major factors associated with hyperuricemia in this study.

语种英语
WOS记录号WOS:000238872000025
引用统计
被引频次:68[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66243
专题北京大学第一临床医学院_内分泌内科
作者单位1.Univ Helsinki, Dept Publ Hlth, FIN-00014 Helsinki, Finland
2.Qingdao Endocrine & Diabet Inst, Qingdao Diabet Epidemiol Study Grp, Qingdao, Peoples R China
3.Natl Publ Hlth Inst, Diabet & Genet Epidemiol Unit, Helsinki, Finland
4.S Ostrobothnia Cent Hosp, Seinajoki, Finland
5.Beijing Univ, First Hosp, Dept Endocrinol, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Nan, Hairong,Qiao, Qing,Dong, Yanhu,et al. The prevalence of hyperuricemia in a population of the coastal city of Qingdao, China[J]. JOURNAL OF RHEUMATOLOGY,2006,33(7):1346-1350.
APA Nan, Hairong.,Qiao, Qing.,Dong, Yanhu.,Gao, Weiguo.,Tang, Bin.,...&Tuomilehto, Jaakko.(2006).The prevalence of hyperuricemia in a population of the coastal city of Qingdao, China.JOURNAL OF RHEUMATOLOGY,33(7),1346-1350.
MLA Nan, Hairong,et al."The prevalence of hyperuricemia in a population of the coastal city of Qingdao, China".JOURNAL OF RHEUMATOLOGY 33.7(2006):1346-1350.
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