IR@PKUHSC  > 北京大学第三临床医学院  > 运动医学研究所
学科主题临床医学
Histological and biomechanical studies of inter-strand healing in four-strand autograft anterior cruciate ligament reconstruction in a rabbit model
Xu, Yan; Ao, Ying-fang
关键词Anterior cruciate ligament Reconstruction Hamstring tendon Braid Histological Biomechanical
刊名KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
2009-07-01
DOI10.1007/s00167-009-0764-6
17期:7页:770-777
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Orthopedics ; Sport Sciences ; Surgery
研究领域[WOS]Orthopedics ; Sport Sciences ; Surgery
关键词[WOS]PATELLAR TENDON ; HAMSTRING TENDONS ; GRAFT ; REVASCULARIZATION ; DOG
英文摘要

In order to observe the remodeling process of the inter-strand of the four-strand graft used for anterior cruciate ligament (ACL) reconstruction, and to find the histological and biomechanical influences on this process by braiding the four-strand graft, we conducted this study in a rabbit model. The rabbit′s ACLs were reconstructed with bilateral four-strand semitendinous tendons which are in parallel or braided shape. The specimens of the two groups were collected at 3, 6, 12, 26 and 52 weeks after the operation. Gross and histological observations were done and the biomechanical properties of the specimens of the 26 and 52 weeks were compared. The result showed that in regular group, at 3 weeks, the strands which were in necrosis status were still separated with each other. At 6 weeks, the grafts were enveloped with hyperplastic synovium, some outer part of the gaps between strands were filled with synovium and fused together, while the inner parts were still separated. At 12 weeks, the graft was still in remodeling progress, but the remodeling degrees of each strand were different. Some strands had fused but some were still separated with "big" interval. At 26 and 52 weeks, some inter-strand gaps were hard to discriminate, some strands were connected with connective tissue and some separated ones still showed up. The braided ones manifested a similar but more synchronized remodeling process and showed a higher inter-strands fusing rate. The biomechanical test showed that the strength of the reconstructed ACL of the regular unbraided tendons was 36% of the contralateral normal ACL, while the braided ones reached 67%. The graft strengths of the specimen of the 26 and 52 weeks in the braided graft group were significantly higher than that of the unbraided group, while the stiffness of the 52-week specimen of the braided group was significantly higher than that of the unbraided group also. From this study, we concluded that as a graft for reconstruction of the ACL, the four-strand hamstring tendon needs to pass through the necrosis, revascularization, and ligamentation progress, but different strands were not in a synchronous process. The inter-strand gap may be completely fused, partial fused, fused but connected with connective tissue or still separated. By braiding the strands, the fusing percentage of the graft could be elevated and the biomechanical properties could be improved.

语种英语
WOS记录号WOS:000267367400009
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66298
专题北京大学第三临床医学院_运动医学研究所
北京大学第三临床医学院_骨科
作者单位Peking Univ, Inst Sports Med, Hosp 3, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Xu, Yan,Ao, Ying-fang. Histological and biomechanical studies of inter-strand healing in four-strand autograft anterior cruciate ligament reconstruction in a rabbit model[J]. KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY,2009,17(7):770-777.
APA Xu, Yan,&Ao, Ying-fang.(2009).Histological and biomechanical studies of inter-strand healing in four-strand autograft anterior cruciate ligament reconstruction in a rabbit model.KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY,17(7),770-777.
MLA Xu, Yan,et al."Histological and biomechanical studies of inter-strand healing in four-strand autograft anterior cruciate ligament reconstruction in a rabbit model".KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY 17.7(2009):770-777.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Xu, Yan]的文章
[Ao, Ying-fang]的文章
百度学术
百度学术中相似的文章
[Xu, Yan]的文章
[Ao, Ying-fang]的文章
必应学术
必应学术中相似的文章
[Xu, Yan]的文章
[Ao, Ying-fang]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。