北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第一临床医学院  > 期刊论文
学科主题: 临床医学
题名:
Liver microcirculation after hepatic artery embolization with degradable starch microspheres in vivo
作者: Wang, Jian; Murata, Satoru; Kumazaki, Tatsuo
刊名: WORLD JOURNAL OF GASTROENTEROLOGY
发表日期: 2006-07-14
卷: 12, 期:26, 页:4214-4218
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology
研究领域[WOS]: Gastroenterology & Hepatology
关键词[WOS]: HEPATOCELLULAR-CARCINOMA ; IODIZED OIL ; LIPIODOL ; CHEMOEMBOLIZATION ; INJECTION ; RAT
英文摘要:

AIM: To observe the dynamic changes of liver microcirculation in vivo after arterial embolization with degradable starch microspheres (DSM).

METHODS: DSM were injected into the proper hepatic artery through a silastic tube inserted retrogradely in gastrocluodenal artery (GDA) of SD rats. Fluorescent microscopy was used to evaluate the dynamic changes of blood flow through the terminal portal venules (TPVs), sinusoids and terminal hepatic venules (THVs). The movements of DSM debris were also recorded. Six hours after injection of DSM, percentages of THVs with completely stagnant blood flow were recorded.

RESULTS: Two phases of blood flow change were recorded. In phase one: after intra-arterial injection of DSM, slow or stagnant blood flow was immediately recorded in TPVs, sinusoids and THVs. This change was reversible, and blood flow resumed completely. In phase two: after phase one, blood flow in TPVs changed again and three patterns of blood flow were recorded. Six hours after DSM injection, 36.9% 9.2% of THVs were found with completely stagnant blood flow.

CONCLUSION: DSM can stop the microcirculatory blood flow in some areas of liver parenchyma. Liver parenchyma supplied by arteries with larger A-P shunt is considered at a higher risk of total microcirculatory blood stagnation after injection of DSM through hepatic artery. (c) 2006 The WIG Press. All rights reserved.

语种: 英语
WOS记录号: WOS:000239997800020
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/66379
Appears in Collections:北京大学第一临床医学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Nippon Med Coll, Dept Radiol, Tokyo 113, Japan
2.Peking Univ, Hosp 1, Dept Intervent Radiol & Vasc Surg, Beijing 100034, Peoples R China

Recommended Citation:
Wang, Jian,Murata, Satoru,Kumazaki, Tatsuo. Liver microcirculation after hepatic artery embolization with degradable starch microspheres in vivo[J]. WORLD JOURNAL OF GASTROENTEROLOGY,2006,12(26):4214-4218.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Wang, Jian]'s Articles
[Murata, Satoru]'s Articles
[Kumazaki, Tatsuo]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Wang, Jian]‘s Articles
[Murata, Satoru]‘s Articles
[Kumazaki, Tatsuo]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2018  北京大学医学部 - Feedback
Powered by CSpace