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Mortality rate prediction by Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM), Portsmouth POSSUM and Colorectal POSSUM and the development of new scoring systems in Chinese colorectal cancer patients
Ren, Lihuan1; Upadhyay, Amit Mani1; Wang, Liang1; Li, Lei1; Lu, Jingqiao2; Fu, Wei1
关键词Colorectal cancer Inpatient mortality POSSUM P-POSSUM Cr-POSSUM
刊名AMERICAN JOURNAL OF SURGERY
2009-07-01
DOI10.1016/j.amjsurg.2008.06.044
198期:1页:31-38
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Surgery
研究领域[WOS]Surgery
关键词[WOS]RISK-ADJUSTED ANALYSIS ; P-POSSUM ; CR-POSSUM ; POSTOPERATIVE MORTALITY ; SURGICAL AUDIT ; COLON-CANCER ; SURGERY ; RESECTION ; PERFORMANCE
英文摘要

BACKGROUND: The aim of this study was to compare the Physiological and Operative Severity Score for the enumeration of Mortality and Morbidity (POSSUM), Portsmouth POSSUM (P-POSSUM), and Colorectal POSSUM (Cr-POSSUM) for predicting surgical mortality in Chinese colorectal cancer patients and to create new scoring systems to achieve better prediction.

METHODS: Data from 903 patients undergoing surgery for colon and rectal cancers from 1992 to 2005 at Peking University Third Hospital were included in this study. POSSUM, P-POSSUM, and Cr-POSSUM were used to predict mortality. Stepwise logistic regression was used to develop the modified P-POSSUM and Cr-POSSUM. Their performances were tested by receiver operating characteristic curve, Hosmer-Lemeshow statistic, and observed: expected ratio.

RESULTS: The actual inpatient mortality was 1.0% (9 of 903). The predicted mortality of POSSUM, P-POSSUM, and Cr-POSSUM were 5.6%, 2.8%, and 4.8%, respectively, which were significantly higher than the actual mortality in Our cohort. The predicted mortality of the modified P-POSSUM and Cr-POSSUM was very close to die observed mortality. Both the modified models offered better accuracy than P-POSSUM.

CONCLUSIONS: The predicted mortality of POSSUM, P-POSSUM, and Cr-POSSUM were significantly higher than the observed mortality in Our patients. The modified P-POSSUM and Cr-POSSUM models provided an accurate prediction of inpatient mortality rate in colorectal cancer patients in China. (C) 2009 Elsevier Inc. All rights reserved.

语种英语
WOS记录号WOS:000267773600006
引用统计
被引频次:17[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66384
专题北京大学第三临床医学院_普通外科
作者单位1.Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100083, Peoples R China
2.Peking Univ, Ctr Clin Epidemiol Res, Hosp 3, Beijing 100083, Peoples R China
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Ren, Lihuan,Upadhyay, Amit Mani,Wang, Liang,et al. Mortality rate prediction by Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM), Portsmouth POSSUM and Colorectal POSSUM and the development of new scoring systems in Chinese colorectal cancer patients[J]. AMERICAN JOURNAL OF SURGERY,2009,198(1):31-38.
APA Ren, Lihuan,Upadhyay, Amit Mani,Wang, Liang,Li, Lei,Lu, Jingqiao,&Fu, Wei.(2009).Mortality rate prediction by Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM), Portsmouth POSSUM and Colorectal POSSUM and the development of new scoring systems in Chinese colorectal cancer patients.AMERICAN JOURNAL OF SURGERY,198(1),31-38.
MLA Ren, Lihuan,et al."Mortality rate prediction by Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM), Portsmouth POSSUM and Colorectal POSSUM and the development of new scoring systems in Chinese colorectal cancer patients".AMERICAN JOURNAL OF SURGERY 198.1(2009):31-38.
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