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学科主题: 临床医学
题名:
Mortality rate prediction by Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM), Portsmouth POSSUM and Colorectal POSSUM and the development of new scoring systems in Chinese colorectal cancer patients
作者: Ren, Lihuan1; Upadhyay, Amit Mani1; Wang, Liang1; Li, Lei1; Lu, Jingqiao2; Fu, Wei1
关键词: Colorectal cancer ; Inpatient mortality ; POSSUM ; P-POSSUM ; Cr-POSSUM
刊名: AMERICAN JOURNAL OF SURGERY
发表日期: 2009-07-01
DOI: 10.1016/j.amjsurg.2008.06.044
卷: 198, 期:1, 页:31-38
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Surgery
研究领域[WOS]: Surgery
关键词[WOS]: RISK-ADJUSTED ANALYSIS ; P-POSSUM ; CR-POSSUM ; POSTOPERATIVE MORTALITY ; SURGICAL AUDIT ; COLON-CANCER ; SURGERY ; RESECTION ; PERFORMANCE
英文摘要:

BACKGROUND: The aim of this study was to compare the Physiological and Operative Severity Score for the enumeration of Mortality and Morbidity (POSSUM), Portsmouth POSSUM (P-POSSUM), and Colorectal POSSUM (Cr-POSSUM) for predicting surgical mortality in Chinese colorectal cancer patients and to create new scoring systems to achieve better prediction.

METHODS: Data from 903 patients undergoing surgery for colon and rectal cancers from 1992 to 2005 at Peking University Third Hospital were included in this study. POSSUM, P-POSSUM, and Cr-POSSUM were used to predict mortality. Stepwise logistic regression was used to develop the modified P-POSSUM and Cr-POSSUM. Their performances were tested by receiver operating characteristic curve, Hosmer-Lemeshow statistic, and observed: expected ratio.

RESULTS: The actual inpatient mortality was 1.0% (9 of 903). The predicted mortality of POSSUM, P-POSSUM, and Cr-POSSUM were 5.6%, 2.8%, and 4.8%, respectively, which were significantly higher than the actual mortality in Our cohort. The predicted mortality of the modified P-POSSUM and Cr-POSSUM was very close to die observed mortality. Both the modified models offered better accuracy than P-POSSUM.

CONCLUSIONS: The predicted mortality of POSSUM, P-POSSUM, and Cr-POSSUM were significantly higher than the observed mortality in Our patients. The modified P-POSSUM and Cr-POSSUM models provided an accurate prediction of inpatient mortality rate in colorectal cancer patients in China. (C) 2009 Elsevier Inc. All rights reserved.

语种: 英语
WOS记录号: WOS:000267773600006
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/66384
Appears in Collections:北京大学第三临床医学院_普通外科_期刊论文

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作者单位: 1.Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100083, Peoples R China
2.Peking Univ, Ctr Clin Epidemiol Res, Hosp 3, Beijing 100083, Peoples R China

Recommended Citation:
Ren, Lihuan,Upadhyay, Amit Mani,Wang, Liang,et al. Mortality rate prediction by Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM), Portsmouth POSSUM and Colorectal POSSUM and the development of new scoring systems in Chinese colorectal cancer patients[J]. AMERICAN JOURNAL OF SURGERY,2009,198(1):31-38.
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