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AgNO3 catalyzed cyclization of propargyl-Meldrum′s acids in aqueous solvent: highly selective synthesis of Z-gamma-alkylidene lactones
Jia, Wei2; Li, Si2; Yu, Miao1; Chen, Wei3; Jiao, Ning2
刊名TETRAHEDRON LETTERS
2009-09-23
DOI10.1016/j.tetlet.2009.07.050
50期:38页:5406-5408
收录类别SCI ; CCR
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Organic
资助者Peking University ; National Science Foundation of China ; National Basic Research Program of China (973 Program) ; Foundation of Ministry of Education of China ; Peking University ; National Science Foundation of China ; National Basic Research Program of China (973 Program) ; Foundation of Ministry of Education of China
研究领域[WOS]Chemistry
关键词[WOS]ONE-POT SYNTHESIS ; ALKYNOIC ACIDS ; STEREOSELECTIVE-SYNTHESIS ; ENOL LACTONES ; DERIVATIVES ; HETEROCYCLIZATION ; BUTYROLACTONES ; CYANOBACTERIN ; PRODUCTS
英文摘要

gamma-Alkylidene lactones have attracted considerable attention due to their diverse biological activities and ubiquitous structural units in natural products. Herein, an efficient AgNO3 catalyzed highly regio- and stereo-selective cyclization Of propargyl-Meldrum′s acids in aqueous solvent was developed, which provides a practical synthetic strategy for the synthesis of substituted Z-gamma-alkylidene butyrolactones tinder neutral reaction conditions. (C) 2009 Elsevier Ltd. All rights reserved.

语种英语
所属项目编号20702002 ; 20872003 ; 2009CB825300 ; 20070001808
资助者Peking University ; National Science Foundation of China ; National Basic Research Program of China (973 Program) ; Foundation of Ministry of Education of China ; Peking University ; National Science Foundation of China ; National Basic Research Program of China (973 Program) ; Foundation of Ministry of Education of China
WOS记录号WOS:000269383200031
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66406
专题北京大学药学院
作者单位1.Chinese Peoples Liberat Army Gen Hosp, Dept Radiol, Beijing 100853, Peoples R China
2.Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
3.Chinese PLA Postgrad Med Sch, Beijing 100853, Peoples R China
推荐引用方式
GB/T 7714
Jia, Wei,Li, Si,Yu, Miao,et al. AgNO3 catalyzed cyclization of propargyl-Meldrum′s acids in aqueous solvent: highly selective synthesis of Z-gamma-alkylidene lactones[J]. TETRAHEDRON LETTERS,2009,50(38):5406-5408.
APA Jia, Wei,Li, Si,Yu, Miao,Chen, Wei,&Jiao, Ning.(2009).AgNO3 catalyzed cyclization of propargyl-Meldrum′s acids in aqueous solvent: highly selective synthesis of Z-gamma-alkylidene lactones.TETRAHEDRON LETTERS,50(38),5406-5408.
MLA Jia, Wei,et al."AgNO3 catalyzed cyclization of propargyl-Meldrum′s acids in aqueous solvent: highly selective synthesis of Z-gamma-alkylidene lactones".TETRAHEDRON LETTERS 50.38(2009):5406-5408.
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