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学科主题临床医学
Recent advances in drug-antibody immunoconjugates for the treatment of cancer
Lam, L; Lam, C; Li, WH; Cao, Y
刊名DRUGS OF THE FUTURE
2003-09-01
28期:9页:905-910
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]METASTATIC BREAST-CANCER ; TECHNOLOGY EVALUATION ; CONJUGATE ; GELDANAMYCIN ; CARCINOMA ; LINKER ; INC
英文摘要

Standard chemotherapy in the treatment of cancer often has a low therapeutic index due to the lack of specificity. Antibody-directed cancer chemotherapy can improve therapeutic indices, with the potential to enhance efficacy and decrease systemic toxicity. Several drug-antibody conjugates have shown impressive antitumor activity in preclinical models and are currently being evaluated in clinical trials. Drug-antibody conjugates may play a substantial role in the future as a single regimen or combination therapy in the treatment of cancer.

语种英语
WOS记录号WOS:000188810400007
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66453
专题北京大学第二临床医学院_皮科
作者单位1.BioMedSci Consulting, Unit 13A, Chicago, IL 60637 USA
2.Univ Chicago Hosp, Dept Pharmaceut Serv, Chicago, IL 60637 USA
3.Peking Univ, Peoples Hosp, Dept Dermatol, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Lam, L,Lam, C,Li, WH,et al. Recent advances in drug-antibody immunoconjugates for the treatment of cancer[J]. DRUGS OF THE FUTURE,2003,28(9):905-910.
APA Lam, L,Lam, C,Li, WH,&Cao, Y.(2003).Recent advances in drug-antibody immunoconjugates for the treatment of cancer.DRUGS OF THE FUTURE,28(9),905-910.
MLA Lam, L,et al."Recent advances in drug-antibody immunoconjugates for the treatment of cancer".DRUGS OF THE FUTURE 28.9(2003):905-910.
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