| 学科主题 | 药学 |
| Synthesis of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma | |
| Li, Q; Li, H; Li, Q; Lou, QH; Su, B; Cai, MS; Li, ZJ | |
| 关键词 | SB1a HCC carbohydrate antigen disulfated tetrasaccharide synthesis |
| 刊名 | CARBOHYDRATE RESEARCH
 |
| 2002-11-19 | |
| 卷 | 337期:21-23页:1929-1934 |
| 收录类别 | SCI ; IC |
| 文章类型 | Article |
| WOS标题词 | Science & Technology |
| 类目[WOS] | Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Organic |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Chemistry |
| 关键词[WOS] | MONOCLONAL-ANTIBODIES ; HEXASACCHARIDE |
| 英文摘要 | A disulfated tetrasaccharide fragment with a spacer arm of human hepatocellular carcinoma carbohydrate antigen SB1a, namely, 2-aminoethyl 3-O-sulfo-beta-D-galactopyranosyl-(1 --> 3)-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1 --> 4)-3-O-sulfo-beta-D-galactopyranosyl-(1 --> 4)-beta-D-glucopyranoside was synthesized via a [2 + 1 + 1] block building mode. In the last coupling step toward the trisaccharide acceptor 8, benzoyl protected galactosyl bromide donor 14 was found to be much more reactive than the acetyl-protected donors. (C) 2002 Elsevier Science Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000179425500003 |
| Citation statistics | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.bjmu.edu.cn/handle/400002259/66498 |
| Collection | 北京大学药学院_化学生物学系 |
| 作者单位 | Peking Univ, Sch Pharmaceut Sci, Dept Biol Chem, Beijing 100083, Peoples R China |
| Recommended Citation GB/T 7714 | Li, Q,Li, H,Li, Q,et al. Synthesis of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma[J]. CARBOHYDRATE RESEARCH,2002,337(21-23):1929-1934. |
| APA | Li, Q.,Li, H.,Li, Q.,Lou, QH.,Su, B.,...&Li, ZJ.(2002).Synthesis of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma.CARBOHYDRATE RESEARCH,337(21-23),1929-1934. |
| MLA | Li, Q,et al."Synthesis of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma".CARBOHYDRATE RESEARCH 337.21-23(2002):1929-1934. |
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