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学科主题临床医学
Disease severity score could not predict the outcomes in peritoneal dialysis-associated peritonitis
Dong, Jie1; Li, Zi1,2; Xu, Rong1; Chen, Yuan1; Luo, Suping1; Li, Yanjun1
关键词peritoneal dialysis peritonitis outcome
刊名NEPHROLOGY DIALYSIS TRANSPLANTATION
2012-06-01
DOI10.1093/ndt/gfr654
27期:6页:2496-2501
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Transplantation ; Urology & Nephrology
研究领域[WOS]Transplantation ; Urology & Nephrology
关键词[WOS]GRAM-NEGATIVE PERITONITIS ; INFECTIONS RECOMMENDATIONS ; CHILDREN ; UPDATE
英文摘要

Background. We aim to explore if disease severity score (DSS) at onset is associated with dialysate white cell counts, the severity of causative organisms and the risk for treatment failure of peritoneal dialysis (PD)-associated peritonitis in an adult PD cohort.

Methods. Our prospective cohort study recorded all peritonitis episodes between 2008 and 2010. The DSS, demographic data and clinical characteristics were recorded at the onset of peritonitis. The dialysate cells were counted at regular intervals and organism culture were examined too. Treatment failure of peritonitis was defined as peritonitis-associated death and transfer to haemodialysis.

Results. A total of 219 episodes of peritonitis in 146 PD patients were recorded, 21.9% of which resulted in treatment failure. There were no significant differences in dialysate white cell counts on the fifth and seventh day and the distribution of causative organism between groups with varied DSS level. DSS could not predict treatment failure including peritonitis-related death and transfer to haemodialysis after adjusting for age, gender, diabetes, dialysis duration, dialysate white cell count on the third day, the presence of Staphylococcus aureus, gram-negative organisms and polymicrobial organisms.

Conclusion. Our study demonstrated that DSS at onset was not associated with prolonged elevation of dialysate white cell counts, severity of causative organisms and outcome of peritonitis episodes in adult PD patients.

语种英语
WOS记录号WOS:000304832100057
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66529
专题北京大学第一临床医学院_肾脏内科
作者单位1.Peking Univ, Med Hosp 1, Div Nephrol, Dept Med, Beijing, Peoples R China
2.Sichuan Univ, W China Hosp, Dept Nephrol, Chengdu, Sichuan, Peoples R China
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GB/T 7714
Dong, Jie,Li, Zi,Xu, Rong,et al. Disease severity score could not predict the outcomes in peritoneal dialysis-associated peritonitis[J]. NEPHROLOGY DIALYSIS TRANSPLANTATION,2012,27(6):2496-2501.
APA Dong, Jie,Li, Zi,Xu, Rong,Chen, Yuan,Luo, Suping,&Li, Yanjun.(2012).Disease severity score could not predict the outcomes in peritoneal dialysis-associated peritonitis.NEPHROLOGY DIALYSIS TRANSPLANTATION,27(6),2496-2501.
MLA Dong, Jie,et al."Disease severity score could not predict the outcomes in peritoneal dialysis-associated peritonitis".NEPHROLOGY DIALYSIS TRANSPLANTATION 27.6(2012):2496-2501.
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