IR@PKUHSC  > 北京大学第三临床医学院  > 普通外科
学科主题临床医学
Application of KNN method to cancer diagnosis using Fourier-transform infrared spectroscopy
Li Xiang; Li Qing-bo; Xu Yi-zhuang; Zhang Guang-jun; Wu Jin-guang; Yang Li-min; Ling Xiao-feng; Zhou Xiao-si; Wang Jian-sheng
关键词KNN cancer FTIR pattern recognition
刊名SPECTROSCOPY AND SPECTRAL ANALYSIS
2007-03-01
27期:3页:439-443
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Spectroscopy
研究领域[WOS]Spectroscopy
关键词[WOS]FTIR SPECTROSCOPY ; OUTLIER DETECTION ; GASTRIC TISSUES ; DISCRIMINATION
英文摘要

Early diagnosis and early medical treatments are the keys to save the patients′ lives and improve their living quality. Fourier transform infrared (FTIR) spectroscopy can be used to distinguish malignant from normal tissues at the molecular level. In the present paper, programs were made with chemometrics method of pattern recognition to classify unknown tissue samples. Spectral data were pretreated by using smoothing, SNV and RHM method. Cross validation was used to test the discrimination effect of KNN method. A total of 63 gastric tissue samples were employed in this study, including 26 cases of normal tissue samples and 37 cases of cancerous tissue samples. The recognition results of the KNN method showed that the correctness of classification achieved 91.7%.

语种中文
WOS记录号WOS:000245492100007
引用统计
被引频次:11[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66668
专题北京大学第三临床医学院_普通外科
作者单位1.Peking Univ, Coll Chem & Mol Engn, State Key Lab Rara Earth Mat & Applicat, Beijing 100871, Peoples R China
2.Beijing Univ Aeronaut & Astronaut, Coll Instrument Sci & Optoelect Engn, Beijing 100083, Peoples R China
3.Peking Univ, Third Hosp, Dept Gen Surg, Beijing 100083, Peoples R China
4.Xian Jiaotong Univ, Dept Surg, First Hosp, Xian 710061, Peoples R China
推荐引用方式
GB/T 7714
Li Xiang,Li Qing-bo,Xu Yi-zhuang,et al. Application of KNN method to cancer diagnosis using Fourier-transform infrared spectroscopy[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS,2007,27(3):439-443.
APA Li Xiang.,Li Qing-bo.,Xu Yi-zhuang.,Zhang Guang-jun.,Wu Jin-guang.,...&Wang Jian-sheng.(2007).Application of KNN method to cancer diagnosis using Fourier-transform infrared spectroscopy.SPECTROSCOPY AND SPECTRAL ANALYSIS,27(3),439-443.
MLA Li Xiang,et al."Application of KNN method to cancer diagnosis using Fourier-transform infrared spectroscopy".SPECTROSCOPY AND SPECTRAL ANALYSIS 27.3(2007):439-443.
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