北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学精神卫生研究所  > 期刊论文
学科主题: 精神卫生
题名:
Revisiting the therapeutic effect of rTMS on negative symptoms in schizophrenia: A meta-analysis
作者: Shi, Chuan1,2,3,4; Yu, Xin3,4; Cheung, Eric F. C.5; Shum, David H. K.6; Chan, Raymond C. K.1,2
关键词: Negative symptoms ; Repetitive transcranial magnetic ; stimulation ; Schizophrenia ; Intervention ; Meta-analysis
刊名: PSYCHIATRY RESEARCH
发表日期: 2014-03-30
DOI: 10.1016/j.psychres.2013.12.019
卷: 215, 期:3, 页:505-513
收录类别: SCI ; SSCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Psychiatry
研究领域[WOS]: Psychiatry
关键词[WOS]: TRANSCRANIAL MAGNETIC STIMULATION ; DORSOLATERAL PREFRONTAL CORTEX ; DOUBLE-BLIND ; 1ST-EPISODE SCHIZOPHRENIA ; POSITIVE SYMPTOMS ; DEFICIT SYNDROME ; CONTROLLED-TRIAL ; PSYCHOSIS ; HYPOFRONTALITY ; INSTRUMENT
英文摘要:

This study sought to determine the moderators in the treatment effect of repetitive transcranial magnetic stimulation (rTMS) on negative symptoms in schizophrenia. We performed a meta-analysis of prospective studies on the therapeutic application of rTMS in schizophrenia assessing the effects of both low-frequency and high-frequency rTMS on negative symptoms. Results indicate that rTMS is effective in alleviating negative symptoms in schizophrenia. The effect size was moderate (0.63 and 0.53, respectively). The effect size of rTMS on negative symptoms in sham-controlled trials was 0.80 as measured by the SANS and 0.41 as measured by the PANSS. A longer duration of illness was associated with poorer efficacy of rTMS on negative symptoms. A 10 Hz setting, at least 3 consecutive weeks of treatment, treatment site at the left dorsolateral prefrontal cortex (DLPFC) and a 110% motor threshold (MT) were found to be the best rTMS parameters for the treatment of negative symptoms. The results of our meta-analysis suggest that rTMS is an effective treatment option for negative symptoms in schizophrenia. The moderators of rTMS on negative symptoms included duration of illness, stimulus frequency, duration of illness, position and intensity of treatment as well as the type of outcome measures used. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

语种: 英语
所属项目编号: XDB02030200 ; 81088001 ; 91132701 ; O7CX031003 ; KSCX2-EW-J-8 ; 2007BAI17B04 ; Y2CX131003 ; D43TW5809
项目资助者: Chinese Academy of Sciences ; National Science Fund China ; Project-Oriented Hundred Talents Programme ; Knowledge Innovation Project of the Chinese Academy of Sciences ; National Key Project of Scientific and Technical Supporting Programs ; Ministry of Science &amp ; Technology of China ; CAS/SAFEA International Partnership Programme for Creative Research Teams ; Fogarty training Grant in Harvard University ; Queensland Smart Futures International Fellowship
WOS记录号: WOS:000333776500002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/66716
Appears in Collections:北京大学精神卫生研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
2.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China
3.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China
4.Univ Chinese Acad Sci, Beijing, Peoples R China
5.Peking Univ, Minist Hlth, Key Lab Mental Hlth, Beijing 100871, Peoples R China
6.Griffith Univ, Griffith Hlth Inst, Behav Basis Hlth Res Program, Gold Coast, Australia

Recommended Citation:
Shi, Chuan,Yu, Xin,Cheung, Eric F. C.,et al. Revisiting the therapeutic effect of rTMS on negative symptoms in schizophrenia: A meta-analysis[J]. PSYCHIATRY RESEARCH,2014,215(3):505-513.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Shi, Chuan]'s Articles
[Yu, Xin]'s Articles
[Cheung, Eric F. C.]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Shi, Chuan]‘s Articles
[Yu, Xin]‘s Articles
[Cheung, Eric F. C.]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2018  北京大学医学部 - Feedback
Powered by CSpace