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学科主题: 临床医学
题名:
Cardiovascular, diabetes, and cancer strips: evidences, mechanisms, and classifications
作者: Hu, Chun-Song1; Wu, Qing-Hua1; Hu, Da-Yi2
关键词: Cardiovascular disease (CVD) ; diabetes ; cancer ; evidence ; mechanisms
刊名: JOURNAL OF THORACIC DISEASE
发表日期: 2014-09-01
DOI: 10.3978/j.issn.2072-1439.2014.07.15
卷: 6, 期:9, 页:1319-1328
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Respiratory System
研究领域[WOS]: Respiratory System
关键词[WOS]: INTIMA-MEDIA THICKNESS ; LONG-TERM RISK ; METABOLIC SYNDROME ; PREVENTING CANCER ; GLUCOSE CONTROL ; BREAST-CANCER ; GROWTH-FACTOR ; ALL-CAUSE ; DISEASE ; MELLITUS
英文摘要:

Objectives: To report and name firstly that there are cardiovascular disease (CVD), diabetes mellitus (DM) and cancers (CDC) strips; and disclose their mechanisms, classifications, and clinical significances.

Study design: Narrative and systematic review study and interpretive analysis.

Methods: Data sources and study selection: to collect and present related evidences on CDC strips from evidence-based, open-access, both Chinese-and English-language literatures in recent 10 years on clinical trials from PubMed according to keywords "CVD, DM and cancers" as well as authors′ extensive clinical experience with the treatment of more than fifty thousands of patients with CVD, diabetes and cancers over the past decades, and analyze their related mechanisms and categories which based on authors′ previous works. Data extraction: data were mainly extracted from 48 articles which are listed in the reference section of this review. Qualitative, quantitative and mixed data were included, narratively and systematically reviewed.

Results: With several conceptual and technical breakthrough, authors present related evidences on CDC strips, these are, CVD and DM, DM and cancers, cancers and CVD linked, respectively; And "Bad SEED" +/- "bad soil" theory or doctrine may explain this phenomenon due to "internal environmental injure, abnormal or unbalance" in human body resulting from the role of risk factors (RFs) related multi-pathways and multitargets, which including organ & tissue (e.g., vascular-specific), cell and gene-based mechanisms. Their classifications include main strips/type B, and Branches/type A as showed by tables and figures in this article.

Conclusions: There are CDC strips and related mechanisms and classifications. CDC strips may help us to understand, prevent, and control related common non-communicable diseases (NCDs) as well as these high risk strips.

语种: 英语
WOS记录号: WOS:000342340800042
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/66758
Appears in Collections:北京大学第二临床医学院_期刊论文

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作者单位: 1.Nanchang Univ, Dept Cardiovasc Med, Nanchang 330006, Peoples R China
2.Peking Univ, Peoples Hosp, Ctr Cardiovasc, Beijing 100044, Peoples R China

Recommended Citation:
Hu, Chun-Song,Wu, Qing-Hua,Hu, Da-Yi. Cardiovascular, diabetes, and cancer strips: evidences, mechanisms, and classifications[J]. JOURNAL OF THORACIC DISEASE,2014,6(9):1319-1328.
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