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学科主题: 临床医学
题名:
Exophiala asiatica, a new species from a fatal case in China
作者: Li, Dong Ming2,3; Li, Ruo Yu1,3; De Hoog, G. S.4; Wang, Yu Xin5; Wang, Duan Li1,3
关键词: Black yeast ; laryngitis ; brain ; Exophiala ; taxonomy
刊名: MEDICAL MYCOLOGY
发表日期: 2009
DOI: 10.1080/13693780802538019
卷: 47, 期:1, 页:101-109
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Mycology ; Veterinary Sciences
研究领域[WOS]: Mycology ; Veterinary Sciences
关键词[WOS]: WANGIELLA-DERMATITIDIS ; SPINIFERA ; FUNGI ; HYDROCARBONS ; JEANSELMEI ; DIVERSITY ; TAXONOMY
英文摘要:

We describe a new species, Exophiala asiatica, isolated from an infection of the pharynx in a 20-year-old, immunocompetent woman in Nanjing, China. The infection was initiated by a fishbone prick in the pharynx, soon developed with facial nodules but subsequently seemed to have disappeared. Tonsil ulceration with progressive soreness of the pharynx was observed 3 years later. Dysphagia, headache and paralysis occurred four years after first signs of infection. Hyphae and yeast-like cells were detected in tissue and a black fungus was recovered repeatedly from pharynx tissue. Despite antifungal therapy for more than one year, the patient died of apparent cerebral dissemination of the etiologic agent. On the basis of morphology, nutritional physiology, ribosomal small subunit DNA and ITS sequence data the strain could not be matched with any existing species. A new species, Exophiala asiatica, is therefore proposed.

语种: 英语
所属项目编号: C30570003
项目资助者: National Natural Science Foundation of China ; China Exchange Programme of the Netherlands Academy of Sciences ; Foundation WOTRO
WOS记录号: WOS:000262057300015
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/66800
Appears in Collections:北京大学第一临床医学院_皮肤性病科_期刊论文

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作者单位: 1.Peking Univ, Res Ctr Med Mycol, Beijing 100034, Peoples R China
2.Cent Bur Schimmelcultures, Utrecht, Netherlands
3.Peking Univ, Hosp 1, Dept Dermatol, Beijing 100034, Peoples R China
4.Peking Univ, Hosp 3, Dept Dermatol, Beijing 100034, Peoples R China
5.Beijing Tongren Hosp, Dept Dermatol, Beijing, Peoples R China

Recommended Citation:
Li, Dong Ming,Li, Ruo Yu,De Hoog, G. S.,et al. Exophiala asiatica, a new species from a fatal case in China[J]. MEDICAL MYCOLOGY,2009,47(1):101-109.
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