IR@PKUHSC  > 北京大学第一临床医学院  > 皮肤性病科
学科主题临床医学
Exophiala asiatica, a new species from a fatal case in China
Li, Dong Ming2,3; Li, Ruo Yu1,3; De Hoog, G. S.4; Wang, Yu Xin5; Wang, Duan Li1,3
关键词Black yeast laryngitis brain Exophiala taxonomy
刊名MEDICAL MYCOLOGY
2009
DOI10.1080/13693780802538019
47期:1页:101-109
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Mycology ; Veterinary Sciences
研究领域[WOS]Mycology ; Veterinary Sciences
关键词[WOS]WANGIELLA-DERMATITIDIS ; SPINIFERA ; FUNGI ; HYDROCARBONS ; JEANSELMEI ; DIVERSITY ; TAXONOMY
英文摘要

We describe a new species, Exophiala asiatica, isolated from an infection of the pharynx in a 20-year-old, immunocompetent woman in Nanjing, China. The infection was initiated by a fishbone prick in the pharynx, soon developed with facial nodules but subsequently seemed to have disappeared. Tonsil ulceration with progressive soreness of the pharynx was observed 3 years later. Dysphagia, headache and paralysis occurred four years after first signs of infection. Hyphae and yeast-like cells were detected in tissue and a black fungus was recovered repeatedly from pharynx tissue. Despite antifungal therapy for more than one year, the patient died of apparent cerebral dissemination of the etiologic agent. On the basis of morphology, nutritional physiology, ribosomal small subunit DNA and ITS sequence data the strain could not be matched with any existing species. A new species, Exophiala asiatica, is therefore proposed.

语种英语
WOS记录号WOS:000262057300015
项目编号C30570003
资助机构National Natural Science Foundation of China ; China Exchange Programme of the Netherlands Academy of Sciences ; Foundation WOTRO
引用统计
被引频次:19[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66800
专题北京大学第一临床医学院_皮肤性病科
作者单位1.Peking Univ, Res Ctr Med Mycol, Beijing 100034, Peoples R China
2.Cent Bur Schimmelcultures, Utrecht, Netherlands
3.Peking Univ, Hosp 1, Dept Dermatol, Beijing 100034, Peoples R China
4.Peking Univ, Hosp 3, Dept Dermatol, Beijing 100034, Peoples R China
5.Beijing Tongren Hosp, Dept Dermatol, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Li, Dong Ming,Li, Ruo Yu,De Hoog, G. S.,et al. Exophiala asiatica, a new species from a fatal case in China[J]. MEDICAL MYCOLOGY,2009,47(1):101-109.
APA Li, Dong Ming,Li, Ruo Yu,De Hoog, G. S.,Wang, Yu Xin,&Wang, Duan Li.(2009).Exophiala asiatica, a new species from a fatal case in China.MEDICAL MYCOLOGY,47(1),101-109.
MLA Li, Dong Ming,et al."Exophiala asiatica, a new species from a fatal case in China".MEDICAL MYCOLOGY 47.1(2009):101-109.
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