IR@PKUHSC  > 北京大学药学院
学科主题药学
Improved synthesis of phytosphingosine and dihydrosphingosine from 3,4,6-tri-O-benzyl-D-galactal
Niu, Youhong2; Cao, Xiaoping2; Ye, Xin-Shan1
刊名HELVETICA CHIMICA ACTA
2008
91期:4页:746-752
收录类别SCI ; IC ; CCR
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]PROTEIN-KINASE-C ; ALPHA-GALACTOSYLCERAMIDE KRN7000 ; BIOLOGICALLY-ACTIVE GLYCOSIDES ; SACCHAROMYCES-CEREVISIAE ; HEPATIC METASTASIS ; SYMBIODINIUM-SP ; NKT CELLS ; STEREOCHEMISTRY ; ANTITUMOR ; MICE
英文摘要

An efficient and facile synthesis of phytosphingosine and dihydrosphingosine derivatives is described with less steps and in improved overall yield (66-72%) starting from commercially available tri-O-benzyl-D-galactal. The key steps include Wittig reaction, Mitsunobu transformation, reduction, and deprotection.

语种英语
WOS记录号WOS:000255731700015
Citation statistics
Cited Times:10[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66804
Collection北京大学药学院
作者单位1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
2.Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
Recommended Citation
GB/T 7714
Niu, Youhong,Cao, Xiaoping,Ye, Xin-Shan. Improved synthesis of phytosphingosine and dihydrosphingosine from 3,4,6-tri-O-benzyl-D-galactal[J]. HELVETICA CHIMICA ACTA,2008,91(4):746-752.
APA Niu, Youhong,Cao, Xiaoping,&Ye, Xin-Shan.(2008).Improved synthesis of phytosphingosine and dihydrosphingosine from 3,4,6-tri-O-benzyl-D-galactal.HELVETICA CHIMICA ACTA,91(4),746-752.
MLA Niu, Youhong,et al."Improved synthesis of phytosphingosine and dihydrosphingosine from 3,4,6-tri-O-benzyl-D-galactal".HELVETICA CHIMICA ACTA 91.4(2008):746-752.
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