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学科主题临床医学
Change of plasma ghrelin level in acute pancreatitis
Liu, Binbin; Liu, Xinguang; Tang, Chaoshu
关键词ghrelin pancreatitis glucose
刊名PANCREATOLOGY
2006
DOI10.1159/000096976
6期:6页:531-535
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Gastroenterology & Hepatology
研究领域[WOS]Gastroenterology & Hepatology
关键词[WOS]RATS ; SECRETION ; PEPTIDE
英文摘要

Background: Ghrelin is a new endogenous ligand for the growth hormone secretagogue receptor and it has many effects, including stimulating appetite, lipid metabolism and gastric motility. We investigated the change of plasma ghrelin concentration in patients with acute pancreatitis. Methods: Blood samples were collected twice from each patient with acute pancreatitis. The first sample was obtained at the time of diagnosis ( before therapy) and the second the day before the patient was dismissed from the hospital ( after recovery). Plasma ghrelin levels were measured with an RIA assay kit and were analyzed with clinical and biochemical parameters. Results: Ghrelin concentration increased from 221.75 +/- 109.69 to 293.38 +/- 156.06 pg/ml when the patients recovered, which had statistical significance. At the same time, the glucose level decreased, but it had no statistical significance. The body mass index (BMI) of the patients did not change either. Conclusions: When the patients with acute pancreatitis recovered, the plasma ghrelin concentration increased significantly. The mechanism of the change in ghrelin level needs further study. Copyright (C) 2006 S. Karger AG, Basel and IAP.

语种英语
WOS记录号WOS:000244258100008
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66813
专题北京大学第一临床医学院_消化科
作者单位Beijing Univ, Hosp 1, Dept Gastroenterol, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Liu, Binbin,Liu, Xinguang,Tang, Chaoshu. Change of plasma ghrelin level in acute pancreatitis[J]. PANCREATOLOGY,2006,6(6):531-535.
APA Liu, Binbin,Liu, Xinguang,&Tang, Chaoshu.(2006).Change of plasma ghrelin level in acute pancreatitis.PANCREATOLOGY,6(6),531-535.
MLA Liu, Binbin,et al."Change of plasma ghrelin level in acute pancreatitis".PANCREATOLOGY 6.6(2006):531-535.
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