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学科主题: 药学
题名:
Xanthone glycosides from herbs of Polygala hongkongensis Hemsl and their antioxidant activities
作者: Wu, Jian-Feng1,2,3,4; Chen, Si-Bao1,5; Gao, Jing-Chun5; Song, Hao-Liang1; Wu, Li-Jun2; Chen, Shi-Lin1,5; Tu, Peng-Fei2,3
关键词: Polygala hongkongensis ; xanthone O-glycosides ; polyhongkongenoside A ; polyhongkongenoside B ; antioxidant activities
刊名: JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
发表日期: 2008
DOI: 10.1080/10286020801967201
卷: 10, 期:7, 页:665-670
收录类别: SCI ; IC
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]: Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]: OLIGOSACCHARIDE ESTERS ; TENUIFOLIA ; SAPONINS ; ROOTS
英文摘要:

Two new xanthone O-glycosides, polyhongkongenosides A (1) and B (2), together with four known xanthone glycosides, were isolated from the herbs of Polygala hongkongensis Hemsl. Their structures were elucidated on the basis of UV, IR, NMR, and MS spectral data. The antioxidant in vitro activities of 1-6 were determined by the scavenging activities against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and hydroxyl radicals and their reductive activities to Fe(3+). Mangiferin, one of the four known xanthone glycosides, showed potential scavenging effect on DPPH and hydroxy radicals and reductive activity to Fe(3+) with IC(50) values of 4.7, 13.9, 23.7 mu M, respectively.

语种: 英语
WOS记录号: WOS:000259658800013
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/66818
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, State Key Lab Chinese Med & Mol Pharmacol, Shenzhen 518057, Peoples R China
2.Shenyang Pharmaceut Univ, Shenyang 110016, Peoples R China
3.Peking Univ, Sch Pharmaceut Sci, Hlth Sci Ctr, Beijing 100083, Peoples R China
4.Foshan Univ, Foshan 528000, Peoples R China
5.Chinese Acad Med Sci, Peking Union Med Coll, Inst Med Plant Dev, Beijing 100094, Peoples R China

Recommended Citation:
Wu, Jian-Feng,Chen, Si-Bao,Gao, Jing-Chun,et al. Xanthone glycosides from herbs of Polygala hongkongensis Hemsl and their antioxidant activities[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2008,10(7):665-670.
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