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Xanthone glycosides from herbs of Polygala hongkongensis Hemsl and their antioxidant activities
Wu, Jian-Feng1,2,3,4; Chen, Si-Bao1,5; Gao, Jing-Chun5; Song, Hao-Liang1; Wu, Li-Jun2; Chen, Shi-Lin1,5; Tu, Peng-Fei2,3
关键词Polygala hongkongensis xanthone O-glycosides polyhongkongenoside A polyhongkongenoside B antioxidant activities
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
2008
DOI10.1080/10286020801967201
10期:7页:665-670
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]OLIGOSACCHARIDE ESTERS ; TENUIFOLIA ; SAPONINS ; ROOTS
英文摘要

Two new xanthone O-glycosides, polyhongkongenosides A (1) and B (2), together with four known xanthone glycosides, were isolated from the herbs of Polygala hongkongensis Hemsl. Their structures were elucidated on the basis of UV, IR, NMR, and MS spectral data. The antioxidant in vitro activities of 1-6 were determined by the scavenging activities against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and hydroxyl radicals and their reductive activities to Fe(3+). Mangiferin, one of the four known xanthone glycosides, showed potential scavenging effect on DPPH and hydroxy radicals and reductive activity to Fe(3+) with IC(50) values of 4.7, 13.9, 23.7 mu M, respectively.

语种英语
WOS记录号WOS:000259658800013
引用统计
被引频次:12[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66818
专题北京大学药学院
北京大学药学院_天然药物学系
作者单位1.Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, State Key Lab Chinese Med & Mol Pharmacol, Shenzhen 518057, Peoples R China
2.Shenyang Pharmaceut Univ, Shenyang 110016, Peoples R China
3.Peking Univ, Sch Pharmaceut Sci, Hlth Sci Ctr, Beijing 100083, Peoples R China
4.Foshan Univ, Foshan 528000, Peoples R China
5.Chinese Acad Med Sci, Peking Union Med Coll, Inst Med Plant Dev, Beijing 100094, Peoples R China
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GB/T 7714
Wu, Jian-Feng,Chen, Si-Bao,Gao, Jing-Chun,et al. Xanthone glycosides from herbs of Polygala hongkongensis Hemsl and their antioxidant activities[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2008,10(7):665-670.
APA Wu, Jian-Feng.,Chen, Si-Bao.,Gao, Jing-Chun.,Song, Hao-Liang.,Wu, Li-Jun.,...&Tu, Peng-Fei.(2008).Xanthone glycosides from herbs of Polygala hongkongensis Hemsl and their antioxidant activities.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,10(7),665-670.
MLA Wu, Jian-Feng,et al."Xanthone glycosides from herbs of Polygala hongkongensis Hemsl and their antioxidant activities".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 10.7(2008):665-670.
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