IR@PKUHSC  > 北京大学第一临床医学院  > 放射治疗科
Collateral Circulation Imaging: MR Perfusion Territory Arterial Spin-Labeling at 3T
Wu, B.1,2; Wang, X.1,2; Guo, J.2; Xie, S.1; Wong, E. C.3,4,5; Zhang, J.2; Jiang, X.1; Fang, J.2
Source PublicationAMERICAN JOURNAL OF NEURORADIOLOGY
2008-11-01
Volume29Issue:10Pages:1855-1860
Indexed BySCI
Abstract

BACKGROUND AND PURPOSE: Current knowledge of the collateral circulation remains sparse, and a noninvasive method to better characterize the role of collaterals is desirable. The aim of our study was to investigate the presence and distal flow of collaterals by using a new MR perfusion territory imaging, vessel-encoded arterial spin-labeling (VE-ASL). MATERIALS AND METHODS: Fifty-six patients with internal carotid artery (ICA) or middle cerebral artery (MCA) stenosis were identified by sonography, VE-ASL was performed to assess the presence and function of collateral flow. The perfusion information was combined with VE maps into high signal-intensity-to-noise-ratio 3-colored maps of the left carotid, right carotid, and posterior circulation territories. The presence of the anterior and posterior collateral flow was demonstrated by the color of the standard anterior cerebral artery/MCA flow territory. The distal function of collateral flow was categorized as adequate (cerebral blood flow [CBF] >= 10 mL/min/100 g) or deficient (CBF <10 mL/min/100 g). The results were compared with those of MR angiography (MRA) and intra-arterial digital subtraction angiography (DSA) in cross table, and K coefficients were calculated to determine the agreement among different methods. RESULTS: The K coefficients of the presence of anterior and posterior collaterals by using VE-ASL and I were 0.785 and 0.700, respectively. The kappa Coefficient of the function of collaterals by using VE-ASL and DSA was 0.726. Apart from collaterals through the circle of Willis, VE-ASL showed collateral flow via leptomeningeal anastomoses. CONCLUSIONS: In patients with ICA or MCA stenosis, VE-ASL could show the presence, the origin, and distal function of collateral flow noninvasively.

Subject Area临床医学
SubtypeArticle
DOI10.3174/ajnr.A1259
WOS HeadingsScience & Technology
Language英语
WOS Research AreaNeurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
WOS SubjectClinical Neurology ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
WOS KeywordBRAIN-FEEDING ARTERIES ; CEREBRAL-ARTERIES ; FLOW PATTERNS ; WILLIS ; CIRCLE ; BLOOD ; ANGIOGRAPHY ; OCCLUSION ; STENOSIS ; STROKE
WOS IDWOS:000261072200010
Citation statistics
Cited Times:42[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.bjmu.edu.cn/handle/400002259/66864
Collection北京大学第一临床医学院_放射治疗科
北京大学第二临床医学院_肾内科
北京大学临床肿瘤学院_日间化疗病区
Affiliation1.Peking Univ, Hosp 1, Dept Radiol, Beijing 100034, Peoples R China
2.Univ Calif San Diego, Ctr Funct Magnet Resonance Imaging, La Jolla, CA 92093 USA
3.Univ Calif San Diego, Dept Radiol, La Jolla, CA 92093 USA
4.Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA
5.Peking Univ, Interdisciplinary Acad, Beijing, Peoples R China
First Author AffilicationPEKING UNIVERSITY HEALTH SCIENCE CENTER
Recommended Citation
GB/T 7714
Wu, B.,Wang, X.,Guo, J.,et al. Collateral Circulation Imaging: MR Perfusion Territory Arterial Spin-Labeling at 3T[J]. AMERICAN JOURNAL OF NEURORADIOLOGY,2008,29(10):1855-1860.
APA Wu, B..,Wang, X..,Guo, J..,Xie, S..,Wong, E. C..,...&Fang, J..(2008).Collateral Circulation Imaging: MR Perfusion Territory Arterial Spin-Labeling at 3T.AMERICAN JOURNAL OF NEURORADIOLOGY,29(10),1855-1860.
MLA Wu, B.,et al."Collateral Circulation Imaging: MR Perfusion Territory Arterial Spin-Labeling at 3T".AMERICAN JOURNAL OF NEURORADIOLOGY 29.10(2008):1855-1860.
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