北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学口腔医学院  > 医学影像科  > 期刊论文
学科主题: 口腔医学
题名:
Cerebral activation during unilateral clenching in patients with temporomandibular joint synovitis and biting pain: an functional magnetic resonance imaging study
作者: Zhao Yan-ping1,2; Ma Xu-chen1,2; Jin Zhen3; Li Ke3; Liu Gang3; Zeng Ya-wei3
关键词: functional magnetic resonance imaging ; unilateral clenching task ; inferior frontal gyrus ; precentral gyrus ; temporomandibular disorders ; synovitis
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2011-07-20
DOI: 10.3760/cma.j.issn.0366-6999.2011.14.011
卷: 124, 期:14, 页:2136-2143
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: POSITRON-EMISSION-TOMOGRAPHY ; CHEWING-SIDE PREFERENCE ; MOVEMENTS ; FMRI ; CLASSIFICATION ; MODULATION ; RESPONSES ; SYMPTOMS ; CORTEX ; FORCE
英文摘要:

Background Functional magnetic resonance is a non-invasive method that can examine brain activity and has been widely used in various fields including jaw movement and pain processing. Temporomandibular disorder (TMD) is one of the most frequent facial pain problems. The objective of this study was to investigate the brain activities using functional magnetic resonance imaging (fMRI) during unilateral maximal voluntary clenching tasks in the TMD synovitis patients with biting pain.

Methods Fourteen TMD synovitis patients with unilateral biting pain and 14 controls were included in the study. Contralateral biting pain was defined as right molar clenching causing left temporomandibular joint (TMJ) pain. Ipsilateral biting pain was defined as right molar clenching causing right TMJ pain. Symptom Check List-90 (SCL-90) was administered to the patients and controls. Independent sample t-test was used to compare the SCL-90 subscales between the two groups. Unilateral clenching tasks were performed by the patients and controls. Imaging data were analyzed using SPM99.

Results Patients were divided into contralateral TMD biting pain group (n=8) and ipsilateral TMD biting pain group (n=6). The SCL-90 subscales were significantly different between the two groups for somatization, depression, anxiety, phobic anxiety, and paranoid ideation. Group analysis of the controls demonstrated brain activations in the inferior frontal gyrus, precentral gyrus, middle frontal gyrus, superior temporal gyrus, and insular. The areas of activation were different between right and left clenching task. In TMJ synovitis patients with contralateral or ipsilateral biting pain, the group analysis showed activations in the inferior frontal gyrus, superior temporal gyrus, medium frontal gyrus, precentral gyrus, and anterior cingulate cortex.

Conclusions The inferior frontal gyrus and precentral gyrus play essential roles during the unilateral clenching task. Activation of anterior cingulate cortex in the synovitis patients with biting pain was associated with higher levels of psychological distress. Chin Med J 2011;124(14):2136-2143

语种: 英语
所属项目编号: IRB00001052-06062
项目资助者: Human Research Ethics Committee at the Peking University Health Science Center
WOS记录号: WOS:000293491100011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/66943
Appears in Collections:北京大学口腔医学院_医学影像科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ Sch & Hosp Stomatol, Dept Oral Radiol, Beijing 100081, Peoples R China
2.Peking Univ Sch & Hosp Stomatol, Ctr Temporomandibular Disorders, Beijing 100081, Peoples R China
3.306 Hosp Peoples Liberat Army, Dept Radiol, Beijing 100101, Peoples R China

Recommended Citation:
Zhao Yan-ping,Ma Xu-chen,Jin Zhen,et al. Cerebral activation during unilateral clenching in patients with temporomandibular joint synovitis and biting pain: an functional magnetic resonance imaging study[J]. CHINESE MEDICAL JOURNAL,2011,124(14):2136-2143.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhao Yan-ping]'s Articles
[Ma Xu-chen]'s Articles
[Jin Zhen]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhao Yan-ping]‘s Articles
[Ma Xu-chen]‘s Articles
[Jin Zhen]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace