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In vitro aging of mineralized collagen-based composite as guided tissue regeneration membrane
Pan, SX; Li, Y; Feng, HL; Bai, W; Gu, YY
关键词guided tissue regeneration (GTR) nano-hydroxyapatite collagen in vitro aging
刊名MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS
2006-05-01
DOI10.1016/j.msec.2005.09.103
26期:4页:724-729
收录类别ISTP ; SCI
文章类型Proceedings Paper
WOS标题词Science & Technology
类目[WOS]Materials Science, Multidisciplinary
研究领域[WOS]Materials Science
关键词[WOS]SCAFFOLDS ; CULTURE ; ACID)
英文摘要

The technique of guided tissue regeneration (GTR) has been developed for the regeneration of periodontal tissues, bone around natural teeth and dental implants. The aim of this study is to investigate the biodegradability and mechanic behavior of a novel mineralized nanohydroxyapatite/collagen/poly (lactic acid) (nHAC/PLA) composite as GTR membrane in vitro. The elastic modulus and maximum tensile strength of GTR film samples with different nHAC/PLA ratio were measured to get an optimal nHAC/PLA ratio. Thermogravimetric analysis was conducted to evaluate the change of the inorganic component in the samples during the process of in vitro aging. Morphology of samples was checked by using scanning electron microscopy. On the basis of the above results, it can be concluded that the GTR membranes maintained integrity and the original appearance throughout the 1-month in vitro aging. There is an active dissolution and deposition process of crystals which is propitious to the bone formation on the surface of the composite membrane. The optimal nHAC/PLA ratio of the novel membrane is 0.4:1. For a longer period of bone repair, PLA with higher molecular weight should be chosen as the scaffold for the GTR membrane. (c) 2005 Elsevier B.V. All rights reserved.

语种英语
WOS记录号WOS:000237640800031
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/66997
专题北京大学口腔医学院_口腔修复科
作者单位1.Peking Univ, Sch Stomatol, Dept Prosthodont, Beijing 100875, Peoples R China
2.Tsing Hua Univ, Dept Mat Sci & Engn, Beijing 100084, Peoples R China
推荐引用方式
GB/T 7714
Pan, SX,Li, Y,Feng, HL,et al. In vitro aging of mineralized collagen-based composite as guided tissue regeneration membrane[J]. MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS,2006,26(4):724-729.
APA Pan, SX,Li, Y,Feng, HL,Bai, W,&Gu, YY.(2006).In vitro aging of mineralized collagen-based composite as guided tissue regeneration membrane.MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS,26(4),724-729.
MLA Pan, SX,et al."In vitro aging of mineralized collagen-based composite as guided tissue regeneration membrane".MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS 26.4(2006):724-729.
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