北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第二临床医学院  > 骨肿瘤科  > 期刊论文
学科主题: 临床医学
题名:
Is total en bloc sacrectomy using a posterior-only approach feasible and safe for patients with malignant sacral tumors?
作者: Zang, Jie; Guo, Wei; Yang, Rongli; Tang, Xiaodong; Li, Dasen
关键词: total en bloc sacrectomy ; sacral tumor ; posterior-only approach ; oncology
刊名: JOURNAL OF NEUROSURGERY-SPINE
发表日期: 2015-06-01
DOI: 10.3171/2015.1.SPINE14237
卷: 22, 期:6, 页:563-570
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Surgery
研究领域[WOS]: Neurosciences & Neurology ; Surgery
关键词[WOS]: EWINGS-SARCOMA ; CONSECUTIVE PATIENTS ; PROGNOSTIC-FACTORS ; CLINICAL-OUTCOMES ; RESECTION ; CHORDOMA ; EXPERIENCE ; RECONSTRUCTION ; NEOPLASMS ; THERAPY
英文摘要:

OBJECT In this study the authors′ aim was to describe their experience with total en bloc sacrectomy using a posterior-only approach and to assess the outcome of patients with malignant sacral tumors who underwent this procedure at their center.

METHODS The authors identified and retrospectively reviewed the records of 10 patients with malignant sacral tumors who underwent a total en bloc sacrectomy via a single posterior approach at their center. The pathological diagnosis was chordoma in 4 patients, chondrosarcoma in 1, osteosarcoma in 1, malignant schwannoma in 1, malignant giant cell tumor in 1, and Ewing′s sarcoma in 2. Radiological examination revealed that the tumor involved S1-5 in 7 patients, S1-4 in 1, S1-3 in 1, and S1-2 in 1.

RESULTS All 10 patients were stable during the perioperative period. The mean surgery duration was 282 minutes (range 250-310 minutes). The median estimated blood loss was 2595 ml (range 1500-3200 ml). All patients were followed up for 13-29 months (mean 22 months). Two patients had a local recurrence. Two patients died of disease, 1 patient was alive with disease, and 7 patients were alive without evidence of disease. Among the 8 surviving patients, 6 were able to walk without assistive devices, and 2 were able to walk with crutches. The total complication rate was 40% (4 of 10). Wound complications (deep infection and wound healing problems) occurred in 3 patients, and a distal deep vein thrombosis occurred in 1 patient.

CONCLUSIONS Total en bloc sacrectomy using a posterior-only approach is feasible and safe in selected patients and is an important procedure for the treatment of primary malignant tumor involving the entire sacrum or only the top portion.

语种: 英语
WOS记录号: WOS:000355031700003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67001
Appears in Collections:北京大学第二临床医学院_骨肿瘤科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Peoples Hosp, Musculoskeletal Tumor Ctr, Beijing 100044, Peoples R China

Recommended Citation:
Zang, Jie,Guo, Wei,Yang, Rongli,et al. Is total en bloc sacrectomy using a posterior-only approach feasible and safe for patients with malignant sacral tumors?[J]. JOURNAL OF NEUROSURGERY-SPINE,2015,22(6):563-570.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zang, Jie]'s Articles
[Guo, Wei]'s Articles
[Yang, Rongli]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zang, Jie]‘s Articles
[Guo, Wei]‘s Articles
[Yang, Rongli]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace