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Characterization of phenolic compounds in the Chinese herbal drug Artemisia annua by liquid chromatography coupled to electrospray ionization mass spectrometry
Han, Jian; Ye, Min; Qiao, Xue; Xu, Man; Wang, Bao-rong; Guo, De-An
关键词Artemisia annua LC-DAD-ESI-MSn phenolic compounds
刊名JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2008-07-15
DOI10.1016/j.jpba.2008.02.013
47期:3页:516-525
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Analytical ; Pharmacology & Pharmacy
研究领域[WOS]Chemistry ; Pharmacology & Pharmacy
关键词[WOS]FLAVONOIDS ; COMPOSITAE ; GLYCOSIDE ; ACIDS ; DIFFERENTIATION ; IDENTIFICATION ; QUADRUPOLE ; ISOMERS ; FLOWERS
英文摘要

A simple and rapid method has been established for the screening of the main phenolic compounds in Artemisia annua by LC-DAD-ESI-MSn. A total of 40 phenolic compounds were identified or tentatively characterized in the methanol extract of A. annua, including 8 C-glycosyl flavonoids, 5 O-glycosyl flavonoids, 3 flavonoid aglycones, 21 quinic acid derivatives, 2 benzoicacid glucosides and 1 coumarin. The C-glycosyl flavonoids were reported from A. annua for the first time and they were found to be a new type of main constituents, and might be responsible for its antioxidant and antiviral activity. Quinic acid derivatives were also found to be the major constituents of A. annua. (C) 2008 Elsevier B.V. All rights reserved.

语种英语
WOS记录号WOS:000256780600009
Citation statistics
Cited Times:72[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67006
Collection北京大学药学院
作者单位Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Han, Jian,Ye, Min,Qiao, Xue,et al. Characterization of phenolic compounds in the Chinese herbal drug Artemisia annua by liquid chromatography coupled to electrospray ionization mass spectrometry[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2008,47(3):516-525.
APA Han, Jian,Ye, Min,Qiao, Xue,Xu, Man,Wang, Bao-rong,&Guo, De-An.(2008).Characterization of phenolic compounds in the Chinese herbal drug Artemisia annua by liquid chromatography coupled to electrospray ionization mass spectrometry.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,47(3),516-525.
MLA Han, Jian,et al."Characterization of phenolic compounds in the Chinese herbal drug Artemisia annua by liquid chromatography coupled to electrospray ionization mass spectrometry".JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 47.3(2008):516-525.
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