IR@PKUHSC  > 北京大学第一临床医学院  > 临床药理研究所
学科主题临床医学
Antimicrobial resistance surveillance of flomoxef in China
Cui, Lanqing; Li, Yun; Lv, Yuan; Xue, Feng; Liu, Jian
关键词Antimicrobial resistance surveillance Flomoxef Minimum inhibitory concentration Susceptibility Resistance
刊名JOURNAL OF INFECTION AND CHEMOTHERAPY
2015-05-01
DOI10.1016/j.jiac.2015.01.008
21期:5-6页:402-404
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Infectious Diseases ; Pharmacology & Pharmacy
研究领域[WOS]Infectious Diseases ; Pharmacology & Pharmacy
关键词[WOS]SPECTRUM BETA-LACTAMASES ; EPIDEMIOLOGY
英文摘要

The aim of this study was to investigate the susceptibility of flomoxef against clinical isolates collected from China and understand the trend of antimicrobial resistance. A total of 2955 pathogenic strains isolated from 18 tertiary hospitals in 18 cities of China over the period from July 2011 to June 2012 were studied. And the susceptibility tests were performed using agar dilution method recommended by CLSI in central laboratory. Flomoxef showed good potency against Enterobacteriaceae with susceptibility rate 85%-100%. The susceptibility rates of flomoxef against Staphylococcus spp. isolates were 63.9%-92.2%; 98.8% of MSSA and 88.2% of MSSE were susceptible to this drug. For other tested bacteria including Moraxella catarrhalis, Haemophilus spp., and Streptococcus spp. (except Viridans group streptococci) flomoxef showed good potency with susceptibility rate more than 95%. All these results strongly suggest that flomoxef is a potent antibacterial agent against major pathogens in China. (C) 2015, Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000356842300015
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67012
专题北京大学第一临床医学院_临床药理研究所
北京大学口腔医学院_口腔预防保健科
作者单位Peking Univ, Hosp 1, Inst Clin Pharmacol, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Cui, Lanqing,Li, Yun,Lv, Yuan,et al. Antimicrobial resistance surveillance of flomoxef in China[J]. JOURNAL OF INFECTION AND CHEMOTHERAPY,2015,21(5-6):402-404.
APA Cui, Lanqing,Li, Yun,Lv, Yuan,Xue, Feng,&Liu, Jian.(2015).Antimicrobial resistance surveillance of flomoxef in China.JOURNAL OF INFECTION AND CHEMOTHERAPY,21(5-6),402-404.
MLA Cui, Lanqing,et al."Antimicrobial resistance surveillance of flomoxef in China".JOURNAL OF INFECTION AND CHEMOTHERAPY 21.5-6(2015):402-404.
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